Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-05-30
2006-05-30
Berch, Mark L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S256000, C514S293000, C514S303000, C514S300000, C514S248000, C546S082000, C546S119000, C546S085000, C546S139000, C544S333000, C544S405000, C544S234000, C544S233000, C544S237000
Reexamination Certificate
active
07053093
ABSTRACT:
Disclosed are compounds of the formula:and the pharmaceutically acceptable salts thereof, wherein W, Q, X, X1, Y and Z are as defined herein. These compounds bind with high selectivity and/or high affinity to the benzodiazepine site of GABAAreceptors and are therefore useful in the treatment of central nervous system (CNS) diseases and as probes for the localization of GABAAreceptors in tissue samples. Also disclosed are intermediates useful in the preparation of these compounds.
REFERENCES:
Chalmers (TiPS vol. 17, pp. 166-172 Apr. 1996).
Albaugh Pamela
Hutchison Alan
Shaw Kenneth
Yuan Jun
Berch Mark L.
Habte Kahsay
McDonnell Boehnen & Hulbert & Berghoff LLP
Neurogen Corporation
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