Antidepressant 2-[(substituted-1-naphthylmethyl)amino]-1-phenylp

Details Antidepressant 2-[(substituted-1-naphthylmethyl)amino]-1-phenylp Antidepressant 2-[(substituted-1-naphthylmethyl)amino]-1-phenylp

1975-05-12

1977-08-16

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260566F, C07C 9122

Patent

active

040426246

ABSTRACT:
Certain 2-[(substituted-1-naphthylmethyl)amino]-1-phenylpropanols of the formula: ##STR1## wherein R' is hydrogen or methoxy and R is hydrogen or 5,8-dichloro possess pharmacological activity as antidepressants.

REFERENCES:
patent: 3873620 (1975-03-01), Pinkas
Zikolova et al., "Tr. Nauchno-Izsled. Inst. Firm", 3, pp. 14-19 (1961).
Klosa, "Journ. fur Prakt. Chemie", vol. 36, pp. 1-4 (1967).
Howe et al., "J. Med. Chem.", vol. 11, No. 5, pp. 1000-1008 (1968).

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