Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-03-21
2006-03-21
Hayes, Robert C. (Department: 1647)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100
Reexamination Certificate
active
07015316
ABSTRACT:
A novel growth factor, persephin, which belongs to the GDNF
eurturin family of growth factors, is disclosed. The human, mouse and rat amino acid sequences have been identified. Human, mouse and rat persephin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using persephin, methods for detecting persephin gene alterations and methods for detecting and monitoring patient levels of persephin are provided. Methods for identifying additional members of the persephin-neurturin-GDNF family of growth factors are also provided.
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DeSauvage Fred
Johnson Eugene M.
Klein Robert
Kotzbauer Paul T.
Lampe Patricia A.
Hayes Robert C.
Thompson & Coburn LLP
Washington University
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