Antigenic peptides derived from telomerase

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Reexamination Certificate

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C530S300000, C514S001000, C514S002600, C514S004300, C514S008100, C514S013800, C424S184100, C424S185100, C436S064000, C436S086000

Reexamination Certificate

active

07030211

ABSTRACT:
This invention relates to proteins or peptides that elicit T cell mediated immunity, and to cancer vaccines and compositions for anti-cancer treatment comprising such proteins or peptide fragments. This invention also relates to pharmaceutical compositions comprising the proteins or peptides and methods for generating T lymphocytes capable of recognizing and destroying tumor cells in a mammal. More specifically, a telomerase protein or peptide for use in a method of treatment or prophylaxis of cancer is provided. In a preferred embodiment, the method comprises generating a T cell response against telomerase.

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HLA Peptide Search Results Ranking Potential 9-mer Peptides Based on a Predicted Half-time Dissociation to HLA Class I Molecule A3 Using the Algorithm available at http://bimas.dcrt.nih.gov/cgi-bin/molbio/ken—parker—combofrom, printed May 7, 2004.
HLA Peptide Search Results Ranking Potential 9-mer Peptides Based on a Predicted Half-time Dissociation to HLA Class I Molecule A—0201 Using the Algorithm available at http://bimas.dcrt.nih.gov/cgi-bin/molbio/ken

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