Microfluidic apparatus for performing gel protein...

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

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C204S613000

Reexamination Certificate

active

07070682

ABSTRACT:
The invention relates to an apparatus for performing gel protein extractions and methods of using the apparatus.

REFERENCES:
patent: 4576702 (1986-03-01), Peck et al.
patent: 5066377 (1991-11-01), Rosenbaum et al.
patent: 5102518 (1992-04-01), Doering et al.
patent: 5217591 (1993-06-01), Gombocz et al.
patent: 5245185 (1993-09-01), Busch et al.
patent: 5275710 (1994-01-01), Gombocz et al.
patent: 5505831 (1996-04-01), Liao et al.
patent: 5541420 (1996-07-01), Kambara
patent: 5587062 (1996-12-01), Togawa et al.
patent: 5599432 (1997-02-01), Manz et al.
patent: 5635045 (1997-06-01), Alam
patent: 5795720 (1998-08-01), Henco et al.
patent: 5916428 (1999-06-01), Kane et al.
patent: 5957579 (1999-09-01), Kopf-Sill et al.
patent: 6013165 (2000-01-01), Wiktorowicz et al.
patent: 6068752 (2000-05-01), Dubrow et al.
patent: 6274089 (2001-08-01), Chow et al.
patent: 6406604 (2002-06-01), Guzman
patent: 6540896 (2003-04-01), Manz et al.
patent: 6592735 (2003-07-01), Meier et al.
patent: WO 94/28406 (1994-12-01), None
patent: WO 98/00231 (1998-01-01), None
patent: WO 00/57170 (2000-09-01), None
CAPLUS abstract for Domingo (ES 2078878 A1).
CAPLUS abstract for Grushka et al. (“Effect of Temperature Gradients on the Efficiency of Capillary Zone Electrophoresis Separations”,Analytical Chemistry, (1989), 61(3); 241-6).
CAPLUS abstract for Guttman et al.(“Effect of Temperature on the Seperation of DNA Restriction Fragments in Capillary Gel Electrophoresis”,Journal of Chromatography, (1991), 559(1-2); 285-94).
CAPLUS abstract for Zhang et al. (“The Effect of Column Temperature on the Migration Teimes of Peptides in Free-Solution Capillary Electrophoresis”,Journal of Liqiud Chromatogrphy, (1993), 16(17): 3689-97.
Gao et al., “High—Throughput Detection of Unknown Mutations by Using Multiplexed Capillary Electrophoresis with Poly(vinylpyrrolidone) Solutions”,Analytical Chemical, vol. 72, No. 11, Jun. 1, 2000, pp. 2499-2506.
Gottschlich et al., “Two-dimensional Electrochromatography/Capillary Electrophoresis on a Microchip”,Analytical Chemistry, vol. 73, No. 11, Jun. 1, 2001, pp. 2669-2674.
Rocklin et al., “A Microfabricated Fluidic Device for Performing Two-Dimensional Liquid-Phase Separations”,Analytical Chemistry, vol. 72, No. 21, Nov. 1, 2000, pp. 5244-5249.
Becker et al., “Planar Quartz Chips with Submicron Channels for Two-Dimensional Capillary Electrophoresis Applications”,J. Micromech. Microeng., vol. 8, 1998, pp. 24-28.
Liu et al., “Two-Dimensional Separations: Capillary Electrophoresis Coupled to Channel Gel Electrophoresis”,Analytical Chemistry, vol. 68, No. 22, Nov. 15, 1996 pp. 3928-3933.
Hillenkamp et al., “Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry of Biopolymers”,Analytical Chemistry, vol. 63, No. 24, Dec. 15, 1991, pp. 1193A-1202A.
Fenselau, “MALDI-MS and Strategies for Protein Analysis”,Analytical Chemistry News&Features, vol. 69, Nov. 1, 1997, pp. 661A-665A.
Kebarle et al., “From Ions in Solution to Ions in the Gas Phase—The Mechanism of Electrospray Mass Spectrometry”,Analytical Chemistry, vol. 65, No. 22, Nov. 15, 1993, pp. 972A-986A.
Yates, III, “Special Feature: Tutorial: Mass Spectrometry and the Age of the Proteome”,Journal of Mass Spectrometry, vol. 33, 1998, pp. 1-19.
Klose et al., “Two-Dimensional Electrophoresis of Proteins: An Updated Protocol and Implications for a Functional Analysis of the Genome”,Electrophoresis, vol. 16, 1995, pp. 1034-1059.
Jungblut et al., “Resolution Power of Two-Dimensional Electrophoresis and Identification of Proteins from Gels”,Electrophoresis, vol. 17, 1996, pp. 839-847.
Rabilloud, “Detecting Proteins Separated by 2-D Gel Electrophoresis”,Analytical Chemistry, vol. 72, Jan. 1, 2000, pp. 48A-55A.
Shevchenko et al., “Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels”,Analytical Chemistry, vol. 68, No. 5, Mar. 1, 1996, pp. 850-858.
Shevchenko et al., “Linking Genome and Proteome by Mass Spectrometry: Large-Scale Identification of Yeast Proteins from Two Dimensional Gels”,Proc. Natl. Acad. Sci. USA, vol. 93, Dec. 1996, pp. 14440-14445.
Gygi et al., “Evaluation of Two-Dimensional Gel Electrophoresis-Based Proteome Analysis Technology”,Proc. Natl. Acad. Sci. USA, vol. 97, No. 17, Aug. 15, 2000, pp. 9390-9395.
Smith, “Probing Proteomes—Seeing the Whole Picture?”,Nature Biotechnology, vol. 18, Oct. 2000, pp. 1041-1042.
Burgi et al., “Optimization in Sample Stacking for High-Performance Capillary Electrophoresis”,Analytical Chemistry, vol. 63, No. 18, Sep. 15, 1991, pp. 2042-2047.
Chien et al., “On-Column Sample Concentration Using Field Amplification in CZE”,Analytical Chemistry, vol. 64, No. 8, Apr. 15, 1992, pp. 489A-496A.
Chien et al., “Sample Stacking of an Extremely Large Injection Volume in High-Performance Capillary Electrophoresis”,Analytical Chemistry, vol. 64, No. 9, May 1, 1992, pp. 1046-1050.
Burgi et al., “On-Line Sample Preconcentration for Capillary Electrophoresis”, inHandbook of Capillary Electrophoresis, Edited by James P. Landers, CRC Press, 1997, pp. 479-493.
Ramsey et al., “Generating Electrospray from Microchip Devices Using Eletroosmotic Pumping”,Analytical Chemistry, vol. 69, No. 6, Mar. 15, 1997, pp. 1174-1178.
Oleschuk et al., “Analytical Microdevices for Mass Spectrometry”,Trends in Analytical Chemistry, vol. 19, No. 6, 2000, pp. 379-388.
Gatlin et al., “Protein Identification at the Low Femtomole Level from Silver-Stained Gels Using a New Fritless Electrospray Interface for Liquid Chromatography—Microspray and Nanospray Mass Spectrometry”,Analytical Biochemistry, vol. 263, 1998, Article No. AB982809, pp. 93-101.
Scheler et al., “Peptide Mass Fingerprint Sequence Coverage from Differently Stained Proteins on Two-Dimensional Electrophoresis Patterns by Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry (MALDI-MS)”,Electrophoresis, vol. 19, 1998, pp. 918-927.
Ramsamooj et al., “Differential Expression of Proteins in Radioresistant and Radiosensitive Human Squamous Carcinoma Cells,”Journal of the National Cancer Institute, vol. 84, No. 8, Apr. 15, 1992, pp. 622-628.
Wilkins et al., “Proteome Research: New Frontiers in Functional Genomics”, Published by Springer, Berlin, 1997, pp. 187-219.
Ostergaard et al., “Psoriasin (S100A7): A Putative Urinary Marker for the Follow-Up of Patients with Bladder Squamous Cell Carcinomas”,Electrophoresis, vol. 20, 1999, 349-354.
Page et al., “Proteomic Definition of Normal Human Luminal and Myoepithelial Breast Cells Purified from Reduction Mammoplasties”,Proc. Natl. Acad. Sci. USA, vol. 96, No. 22, Oct. 26, 1999, pp. 12589-12594.
Wilm et al., “Femtomole Sequencing of Proteins from Polycrylamide Gels by Nano-Electrospray Mass Spectrometry”,Nature, vol. 379, Feb. 1, 1996, pp. 466-469.
Lottspeich, “Proteome Analysis: A Pathway to the Functional Analysis of Proteins”,Angew. Chem. Int. Ed., vol. 38, 1999, pp. 2476-2492.
Pandey et al., “Proteomics to Study Genes and Genomes”,Nature, vol. 405, Jun. 15, 2000, pp. 837-846.
Binz et al., “A Molecular Scanner to Automate Proteomic Research and to Display Proteome Images”,Analytical Chemistry, vol. 71, No. 21, Nov. 1, 1999, pp. 4981-4988.
Bienvenut et al., “Toward a Clinical Molecular Scanner for Proteome Research: Parallel Protein Chemical Processing Before and During Western Blot”,Analytical Chemistry, vol. 71, No. 21, Nov. 1, 1999, pp. 4800-4807.
Hjerten et al., “Adaptation of the Equipment for High-Performance Electrophoresis to Isoelectric Focusing”,Journal of Chromatography, vol. 346, 1985, pp. 265-270.
Hjerten et al., “Carrier-Free Zone El

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