Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-04
2006-07-04
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S280000
Reexamination Certificate
active
07071199
ABSTRACT:
The present application is directed to a compound of Formula (I) as defined herein which are useful as kinase inhibitors.
REFERENCES:
patent: 4140851 (1979-02-01), Townsend
patent: 4229453 (1980-10-01), Roth et al.
patent: 4892865 (1990-01-01), Townsend et al.
patent: 4927830 (1990-05-01), Townsend et al.
patent: 4968686 (1990-11-01), Townsend et al.
patent: 4996206 (1991-02-01), Taylor et al.
patent: 5028608 (1991-07-01), Taylor et al.
patent: 5248775 (1993-09-01), Taylor et al.
patent: 5254687 (1993-10-01), Taylor et al.
patent: 5344932 (1994-09-01), Taylor
patent: 5349064 (1994-09-01), Akimoto et al.
patent: 5416211 (1995-05-01), Barnett et al.
patent: 5593997 (1997-01-01), Dow et al.
patent: 5594121 (1997-01-01), Froehler et al.
patent: 5612482 (1997-03-01), Barnett et al.
patent: 5639757 (1997-06-01), Dow et al.
patent: 5644057 (1997-07-01), Yuan et al.
patent: 5644058 (1997-07-01), Barnett et al.
patent: 5665721 (1997-09-01), Bhagwat et al.
patent: 5686457 (1997-11-01), Traxler et al.
patent: 5721356 (1998-02-01), Ugarkar et al.
patent: 5726302 (1998-03-01), Ugarkar et al.
patent: 5763596 (1998-06-01), Boyer et al.
patent: 5763597 (1998-06-01), Ugarkar et al.
patent: 5834469 (1998-11-01), Elliott et al.
patent: 3036390 (1982-05-01), None
patent: 0402903 (1990-12-01), None
patent: 0496617 (1992-07-01), None
patent: 0795556 (1997-09-01), None
patent: 94/17803 (1994-08-01), None
patent: 96/10028 (1996-04-01), None
patent: 96/31510 (1996-10-01), None
patent: 96/40686 (1996-12-01), None
patent: 96/40705 (1996-12-01), None
patent: 96/40706 (1996-12-01), None
patent: 96/40707 (1996-12-01), None
patent: 96/02266 (1997-01-01), None
patent: 97/03069 (1997-01-01), None
patent: 97/13771 (1997-04-01), None
patent: 97/28161 (1997-08-01), None
patent: 97/32879 (1997-09-01), None
patent: 97/34895 (1997-09-01), None
patent: WO 97/49706 (1997-12-01), None
patent: 98/41525 (1998-09-01), None
patent: 00/44728 (2000-08-01), None
Hanke, J.H. et al., “Discovery of a Novel, Potent and Src Family-selective Tyrosine Kinase Inhibitor”, J. Biol. Chem., 271(2):695-701, (1996).
Missbach, M. et al., “A Novel Inhibitor of the Tyrosine Kinase Src Suppresses Phosphorylation of its Major Cellular Substrates and Reduces Bone Resorption In Vitro and in Rodent Models In Vivo”, Bone, 24(5):437-449. (1999).
Traxler, P.M. et al., “4-(Phenylamino)pyrrolopyrimidines: Potent and Selective, ATP Site Directed Inhibitors of the EGF-Receptor Protein Tyrosine Kinase”, J. Med. Chem., 39: 2285-2292, (1996).
Showlater, H.D.H. et al., “Synthesis and SAR for a Series of 4-substituted 1H-pyrimido [4,5-b] and SH-pyrimido [5, 4-b] indoles as EGF Receptor Tyrosine Kinase Inhibitors”, Proceedings of the American Association for Cancer Research, 37, Mar. 1996, (abstract).
Dave, C.G. et al., “Synthesis & Biological Activity of Pyrrolo[2, 3-d] Pyrimidines”, Indian J. Chem., 27B:778-780, (1988).
Calderwood David
Hirst Gavin C.
Rafferty Paul
Ritter Kurt
St. Gallay Stephen
Abbott GmbH & CCo. KG
Conway John D.
Kifle Bruck
O'Brien Gayle B.
LandOfFree
Kinase inhibitors as therapeutic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Kinase inhibitors as therapeutic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kinase inhibitors as therapeutic agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3608793