Synthesis of quetiapine and pharmaceutically acceptable...

Details Synthesis of quetiapine and pharmaceutically acceptable... Synthesis of quetiapine and pharmaceutically acceptable...

2006-07-04

2006-07-04

Coleman, Brenda (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07071331

ABSTRACT:
Provided is a novel synthesis of quetiapine employing phase transfer catalyst.

REFERENCES:
patent: 4879288 (1989-11-01), Warawa et al.
patent: 0 240 228 (1987-10-01), None
patent: 0 282 236 (1988-09-01), None
patent: WO 99/06381 (1999-02-01), None
patent: WO 01/55125 (2001-08-01), None
patent: WO 03/080065 (2003-10-01), None
Merck Index, 13thEdition, 8130 (2001).
Warawa E. J. et al., “Behavioral approach to nondyskinetic dopamine antagonists: Identification of Seroquel”J. Med. Chem. 2001, 44,372-389.

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