Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-06-06
1997-04-15
Wilson, James O.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 245, 536 2533, 536 2534, A61K 3170, C07H 2100
Patent
active
056209630
ABSTRACT:
Sequence-specific phosphorothioate oligonucleotides comprising nucleoside units which are joined together by either substantially all Sp or substantially all Rp phosphorothioate intersugar linkages are provided. Such sequence-specific phosphorothioate oligonucleotides having substantially chirally pure intersugar linkages are prepared by enzymatic or chemical synthesis. They are especially well suited as diagnostics, therapeutics and research reagents in instances of cancer mediated by PKC-.alpha..
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Cook Phillip D.
Hoke Glenn
ISIS Pharmaceuticals Inc.
Wilson James O.
LandOfFree
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