Herbal composition PHY906 and its use in chemotherapy

Details Herbal composition PHY906 and its use in chemotherapy Herbal composition PHY906 and its use in chemotherapy

2006-04-11

2006-04-11

Leith, Patricia (Department: 1654)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Reexamination Certificate

active

07025993

ABSTRACT:
This invention provides herbal compositions useful for increasing the therapeutic index of drugs, including those used in the treatment of disease, especially viral infections and neoplasms of cancer. This invention provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a person undergoing such chemotherapy.

REFERENCES:
patent: 4613591 (1986-09-01), Aburada et al.
patent: 4618495 (1986-10-01), Okuda et al.
patent: 5437866 (1995-08-01), Sun
patent: 5665393 (1997-09-01), Chen et al.
patent: 6048847 (2000-04-01), Ramadoss et al.
Huey Liu Shwu et al., “Prevention of CPT-11 Induced Toxicity by a Chinese Medicinal Formulation, PHY-906”. Proceedings of the American Association for Cancer Research Annual, No. 41, Mar. 2000, p. 410, XP001018859.
Shwu-Huey Liu et al., “A Chinese Medicine Formulation, PHY-906, Can Enchance The Therapeutic Index of CPT-11 and other Anticancer Drugs Against Cancer in Mice”. Proceedings of the American Association for Cancer Research Annual, vol. 42, Mar. 2001, p. 85, XP001018879.
M. Narita et al., “Inhibition of Beta-Glucuronidase by Natural Glucurondes of Kampo Medicines Using Glucuronide of SN-38(7-ETHYL-10-Hydroxycamptothecin) as a Substrate”, Xenobiotia, vol. 23, No. 1, 1993, p. 5-10, XP001022293.
Kiyoshi Takasuna et al., “Protective Effects of Kampo Medicines and Baicalin Against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT-11), in Rats”, Japanese Journal of Cancer Research, vol. 86, No. 10, 1995, p. 978-984, XP001022186.
K. Mori et al., “Kampo Medicines for the Prevention of Irinotecan —Induced Diarrhea in Advanced Non-Small cell Lung Cancer”, Gan T Kagaku Ryoho Japanese Journal of Cancer and Chemotherapy, (Jul. 1998) 25 (8) 1159-63, XP001022284.
R. M. Goldberg et al., “Irinotecan Plus 5-Fu and Leucovorin in Advanced Colorectal Cancer: North American Trials” Oncology, S. Karger Ag, Basel, CH, vol. Suppl. 6, No. 6, Aug. 1998, p. 59-63.
Bleiberg H., European J. of Cancer, 35(3), 371-379, 1999.
Govindarajan et al., Lancet, 356:566, 2000 (Aug. 12).
Stucky-Marshall L., Cancer Nursing, 22(3), 212, 1999.

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