Human cripto-related gene

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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Details

4352523, 4353201, 536 235, C12N 1512, C12N 510

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active

056208669

ABSTRACT:
The present invention relates, in general, to a human CRIPTO-related gene. In particular, the present invention relates to a DNA segment encoding a human CRIPTO-related gene; polypeptides encoded by that DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a human CRIPTO-related polypeptide; a DNA segment encoding a genomic clone of the human CRIPTO gene (CR-1); antibodies specific to CR-3; and a method of measuring the amount of CR-3 in a sample.

REFERENCES:
patent: 5256643 (1993-10-01), Perisco et al.
Ciccodicola, Alfredo, et al. (1989) "Molecular characterization of a gene of the `EGF family` expressed in undifferentiated human NTERA2 teratocarcinoma cells", The EMBO Journal, 8:1987-1991.
Dono et al Am. J. Hum. Genet. 49 555-65 (1991).
Wallace et al Meth. Enzymol. 152 432-42 (1987).

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