DNA molecules encoding L-glutamate-gated chloride channels...

Details DNA molecules encoding L-glutamate-gated chloride channels... DNA molecules encoding L-glutamate-gated chloride channels...

2006-04-25

2006-04-25

Mertz, Prema (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S071100, C435S071200, C435S252300, C435S254110, C435S320100, C435S325000, C435S471000, C530S350000

Reexamination Certificate

active

07033789

ABSTRACT:
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encodeSchistocerca americana(grasshopper) glutamate-gated chloride channels. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encodingS. americanaglutamate-gated chloride channels, substantially purified forms of associatedS. americanaglutamate-gated chloride channels and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associatedSchistocerca americanaglutamate-gated chloride channels, which will be useful as insecticides.

REFERENCES:
patent: 5527703 (1996-06-01), Cully et al.
Eck & Wilson in Goodman & Gilman's The Pharmacological Basis of Therapeutics, Ninth Edition, McGraw-Hill New York, 1996.
Mikayama et al. Proc. Natl. Acad. Sci. USA vol. 90, pp. 10056-10060.
Voet et al. Biochemistry John Wiley & Sons, Inc., pp. 126-128 and 228-234.
Dudel, etal.: “Chloride channels gated by extrajunctional glutamate receptors (H-receptors) on locust leg muscle”; Brain Research, vol. 481, pp. 215-220, 1989.
Lingel, etal.: “A glutamate-activated chloride conductance on a crustacean muscle”; Brain Research, vol. 212, pp. 481-488, 1981.
Horseman, etal.: “The effects of L-glutamate on cultured insect neurones”; Neurosciences Letters, vol. 85, pp. 65-70, 1988.
Wafford and Sattelle.: “L-Glutamate Receptors on the Cell Body Membrane of an Identified Insect Motor Neurone”; J. Exp. Biol., vol. 144, pp. 449-462, 1989.
Lea and Usherwood.: “The Site of Action of Ibotenic Acid and the Indentification of Two Populations of Glutamate Receptors on Insect Muscle-Fibres”; Comp. Gen. Pharmac., vol. 4, pp. 333-350, 1973.
Cullcandy.: “Two Types of Extrajunctional L.-Glutamate Receptors in Locust Muscle Fibres”; J. Physiol., vol. 255, pp. 449-464, 1976.
Cully, etal.: “Cloning of an avermetinsensitive glutamate-gated chloride channel fromCaenorhabditis elegans”; Nature, vol. 371, pp. 707-711, 1994.
Arena, etal.: “Expression of a Glutamate-activated Chloride current inXenopus oocytesinjected withCaenorhabditis elegansRNA; evidence of modulation by avermectin”; Molecular Brain Research, vol. 15, pp. 339-348, 1992.
Cully, etal.: “Identification of aDrosophila melanogasterGlutamate-gated chloride Channel Sensitive to the Antiparasitic Agent Avermectin”; J. Biol. Chem., vol. 271, pp. 20187-20191, 1996.
Raymond, etal.: “Co-existence in DUM neurones of two GluCl channels that differ in their picrotoxin sensitivity”, Neuropharmacology, vol. 11, No. 12, 1pp. 2695-2701, 2000.

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