Methods for screening compounds that bind human COE-2

Details Methods for screening compounds that bind human COE-2 Methods for screening compounds that bind human COE-2

2006-07-25

2006-07-25

Spector, Lorraine (Department: 1647)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007210, C435S226000, C436S501000, C530S350000, C536S023200

Reexamination Certificate

active

07081344

ABSTRACT:
The invention provides isolated nucleic acid molecules, designated COE-2 nucleic acid molecules, which encode novel carboxylesterase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing COE-2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a COE-2 gene has been introduced or disrupted. The invention still further provides isolated COE-2 proteins, fusion proteins, antigenic peptides and anti-COE-2 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

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