PRO 703 nucleic acids

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S070100, C435S320100, C435S325000, C536S023500

Reexamination Certificate

active

07074593

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: 6288213 (2001-09-01), Stahl et al.
patent: WO 99/36537 (1999-07-01), None
Strausberg et al. National Cancer Institute, Cancer Genome Anatomy Project (CGAP), Tumor Gene Index (1997), AA614445.
Dayhoff, Accession No.: P_AAB60388, WO 200104301-A1, Pub Date: Jan. 18, 2001, Morikawa, N., et al.
Dayhoff, Accession No.: P_AAB83279, WO 200121795-A2, Pub Date: Mar. 29, 2001, Stahl, A., et al.
Dayhoff, Accession No.: P_AAB24054, WO 200053754-A1, Pub Date: Sep. 14, 2000, Baker, K.P., et al.
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Dayhoff, Accession No.: P_AAY41699, WO 9946281-A2, Pub Date: Sep. 16, 1999, Wood, W.I., et al.
Dayhoff, Accession No.: CAC36515.1, WO 0121795-A, Pub Date: Mar. 29, 2001, Stahl, A., et al.
Dayhoff, Accession No.: AAH09916.1, Direct Submission, Submitted: Jul. 2, 2001, Strausberg, R. et al.
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Dayhoff, Accession No.: P_AAB83278, WO 200121795-A2, Pub Date: Mar. 29, 2001, Stahl, A., et al.
Dayhoff, Accession No.: P_AAY14969, WO 9936537-A2, Pub Date: Jul. 22, 1999, Stahl, A., et al.
Dayhoff, Accession No.: CAC36514.1, WO 0121795-A1, Pub Date: Mar. 29, 2001, Stahl, A., et al.
Dayhoff, Accession No.: P_AAG62172, WO 200132910-A2, Pub Date: May 10, 2001, Ruben, S.M., et al.
GenBank, Accession No.: P_AAC58239, WO 200053754-A1, Pub Date: Sep. 14, 2000, Baker, K.P., et al.
GenBank, Accession No.: BC003041, Proc. Natl. Acad. Sci. U.S.A., 99 (26), pp. 16899-16903, 2002, Strausberg, R.L., et al.
GenBank, Accession No.: BC009916, Proc. Natl. Acad. Sci. U.S.A., 99 (26), pp. 16899-16903, 2002, Strausberg, R.L., et al.
GenBank, Accession No.: AAF27417, WO 200104301-A1, Pub Date: Jan. 18, 2001, Morikawa, N., et al.
GenBank, Accession No.: AX101424, WO 0121795-A1, Pub Date: Mar. 29, 2001, Stahl, A., et al.
GenBank, Accession No.: P_AAH17621, EP 1074617-A2, Pub Date: Feb. 7, 2001, Ota, T., et al.
GenBank, Accession No.: AK027499, Nat. Genet. 36 (1), pp. 40-45, 2004, Ota, T., et al.
GenBank, Accession No.: P_AAH19223, WO 200132910-A2, Pub Date: May 10, 2001, Ruben, S.M., et al.
GenBank, Accession No.: P_AAF89041, WO 200121795-A2, Pub Date: Mar. 29, 2001, Stahl, A., et al.
GenBank, Accession No.: P_AAZ00379, WO 9936537-A2, Pub Date: Jul. 22, 1999, Stahl, A., et al.
GenBank, Accession No.: AX101409, WO 0121795-A1, Pub Date: Mar. 29, 2001, Stahl, A., et al.
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eu Breat Cancer Predictive Testing”, Oathology Associates Medical Laboratores, (Aug. 1999).
Hyman, Elizabeth, et al., “Impact of DNA Amplification on Gene Expression Patterns in Breast Cancer1,2”,Cancer Research62 6240-6245, (Nov. 2002).
Orntoft, Torben F., et al., “Genome-wide Study of Gene Copy Numbers, Transcripts , and Protein Levels in Pairs of Non-Invasive and Invasive Human Transitional Cell Carcinomas”,Molecular&Cellular Proteomics1:37-45, (2002).
Pollack, Jonathan R., et al., “Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors”,PNASvol. 99, 20:12963-12968, (Oct. 2002).
Hillier, L. et al., “zn92e09.s1 Stratagene Lung Carcinoma 937218 3' Similar to TR: G563829 G563829 Fatty Acid Transport Protein; mRNA Sequence”, Accession No.: AA127444, Dec. 5, 1996, Unpublished.
Hillier, L. et al., “aa12f02.r1 Soares_NhHMPu_s1Homo sapienscDNA clone Image: 813051 5' Similar to TR: G563829 G563829 Fatty Acid Transport Protein; mRNA Sequence”, Accession No.: AA458592, Jun. 13, 1997.
Hillier, L. et al., “zc44h06.r1 Soares_senescent-fibroblasts_NbHSFHomo sapienscDNA clone Image: 325211 5' similar to PIR: A55093 A55093 Fatty Acid Protein Precursor—mouse; mRNA Sequence”, Accession No.: W48808, May 30, 1996, Unpublished.
Hirsch et al., “A family of fatty acid transporters conserved from mycobacterium to man”,Proc. Natl. Acad. Sci.,vol. 95, pp. 8625-8629, Jul. 1998.
Stahl, A. et al., “Fatty Acid Transport Proteins”, Sequence ID's 10, 11, 54, 55 and 73, Accession Nos.: AR193703, AAE92253 and Second Sequence: DNA50913, Published: WO 99/36537, Jul. 22, 1999.
Blast Results A1-A35 (Alignment of DNA50913 and various nucleotide sequences—GenBank Database), Oct. 4, 2001.
Blast Results B1-B15 (Alignment of DNA50913 and various polypeptide sequences—Dayhoff Database), Oct. 3, 2001.
Uchida et al.,J Biochem(Tokyo) 119(3):565-571 (1996) and Uchiyama et al.,J Biol Chem271(48):30360-30365 (1996).

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