Drug delivery system for hydrophobic drugs

Details Drug delivery system for hydrophobic drugs Drug delivery system for hydrophobic drugs

2006-01-10

2006-01-10

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C424S001210, C514S410000, C514S937000

Reexamination Certificate

active

06984395

ABSTRACT:
Compositions comprising microaggregates containing hydrophobic drugs, as well as methods for their production, are described. Such microaggregates may include micelle structures or combinations thereof with liposomes, and constitute an effective delivery vehicle for a hydrophobic agent. Methods for microaggregate production include the use of preferred lipid compounds and processing conditions favoring the production of small aggregates for improved filter sterilization.

REFERENCES:
patent: 4512762 (1985-04-01), Spears
patent: 4577636 (1986-03-01), Spears
patent: 4649151 (1987-03-01), Dougherty et al.
patent: 4753788 (1988-06-01), Gamble
patent: 4753958 (1988-06-01), Weinstein et al.
patent: 4776991 (1988-10-01), Farmer et al.
patent: 4866168 (1989-09-01), Dougherty et al.
patent: 4883790 (1989-11-01), Levy et al.
patent: 4889129 (1989-12-01), Dougherty et al.
patent: 4920143 (1990-04-01), Levy et al.
patent: 4932934 (1990-06-01), Dougherty et al.
patent: 4946683 (1990-08-01), Forssen
patent: 5010073 (1991-04-01), Kappas et al.
patent: 5095030 (1992-03-01), Levy et al.
patent: 5096629 (1992-03-01), Nanba et al.
patent: 5171749 (1992-12-01), Levy et al.
patent: 5257970 (1993-11-01), Dougherty
patent: 5270053 (1993-12-01), Schneider et al.
patent: 5320906 (1994-06-01), Eley et al.
patent: 5329029 (1994-07-01), Wan
patent: 5389378 (1995-02-01), Madden
patent: 5435989 (1995-07-01), Presant et al.
patent: 5707608 (1998-01-01), Liu
patent: 5879703 (1999-03-01), Fountain
patent: 5880145 (1999-03-01), Sternberg et al.
patent: 5885557 (1999-03-01), Lentini
patent: 5922355 (1999-07-01), Parikh et al.
patent: 5929105 (1999-07-01), Sternberg et al.
patent: 5990149 (1999-11-01), Sternberg et al.
patent: 6074666 (2000-06-01), Desai et al.
patent: 6153639 (2000-11-01), Sternberg et al.
patent: 6375930 (2002-04-01), Young
patent: WO 97/04746 (1997-02-01), None
patent: WO 98/48621 (1998-11-01), None
patent: WO 00/34763 (2000-06-01), None
patent: WO 01/85213 (2001-11-01), None
Brodin et al., Acta Pharm. Suec. (1982) 19:267-284.
Cozzani et al., In Porphyrins in Tumor Phototherapy, 177-183, Plenum Press (Andreoni et al. eds. 1984).
Diamond et al., Lancet, (1972) 2:1175-77.
Dougherty et al., “The Science of Photo Medicine”, 625-38 (Regan et al. eds. 1982).
Dougherty et al., “Cancer: Principles and Practice of Oncology”, 1836-44 (DeVita Jr. et al. eds. 1982).
Fung et al., Biomater. Artif. Cells. Artif. Organs (1988) 16:439 et. seq.
Johnson et al., Proc. Photodymanic Therapy: Mechanisms II, Proc. SPIE-Int. Soc. Opt. Eng., (1990) 1203:266-80.
Jori et al., Br. J. Cancer, (1983) 48:307-309.
Lasic, Nature (1992) 355:379-380.
Moon and Giddings, J. Pharm. & Biomed. Analysis, (1993) 11:911-20.
Lipson et al., J. Natl. Cancer Inst., (1961) 26:1-8.
Madden et al., Biochemistry (1988) 27:8724-8730.
Milanesi, Int. J. Radiat. Biol. (1989) 55:59-69.
Redmond and Gamlin, Photochem. Photobiol. (1999) 70(4):391-475.
Ricchelli, New Directions in Photodynamic Therapy (1987) 847:101-106.
Supersaxo et al., Pharm. Res. (1991) 8:1286-1291.
Weishaupt et al., Cancer Research (1976) 36:2326-29.
Yokoyama et al., Cancer Res. (1991) 51:3229-3236.
Zhou et al., Photochemistry and Photobiology, (1988) 48:487-92.
Tatman, D., et al., “Carotenohematoporphyrins as Tumor—Imaging Dyes. Synthesis and In Vitro Photophysical Characterization” Photochemistry and Photobiology 68(4):459-466 (1998).

Affiliated with

Also associated with

Rating

Drug delivery system for hydrophobic drugs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Drug delivery system for hydrophobic drugs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Drug delivery system for hydrophobic drugs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3591059