Method for delivering nonaqueous fluorinated drug delivery vehic

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

424427, 424426, 424423, 424434, 424435, 424501, 514912, 514963, A61K 910, A61K 914, A61K 4724

Patent

active

056206992

ABSTRACT:
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone liquid carriers. The suspended drug delivery vehicles may be water labile or water stable and incorporate therapeutic or diagnostic compounds which remain stable and pharmaceutically effective for extended periods. The pharmaceutical compositions have improved bioavailability, are capable of low dose volume delivery, and do not leach the incorporated therapeutic or diagnostic compounds into the liquid carriers making them well suited for multi-dose packaging and administration.

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