Angiopoietins and methods of treating hypertension

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...

Reexamination Certificate

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C514S012200, C530S388220, C530S391100, C530S501000

Reexamination Certificate

active

07052695

ABSTRACT:
The invention generally relates to angiogenic factors and more particularly to the angiopoietin family of growth factors and to methods of using these growth factors to induce vasodilation and hypotension and reducing hypertension.

REFERENCES:
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patent: WO 98/05779 (1998-02-01), None
patent: WO 00/37642 (2000-06-01), None
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Kido et al., Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents, J. Thor. Cardiovascular Surg. 129:268-76, Feb 2005.
Rudge et al., Angiopoietin-1 and pulmonary hypertension: Cause or Cure? Circ. Res. 92:947-949, 2003.
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