Substituted alcohols useful in treatment of Alzheimer's disease

Details Substituted alcohols useful in treatment of Alzheimer's disease Substituted alcohols useful in treatment of Alzheimer's disease

2006-01-03

2006-01-03

Raymond, Richard L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S248000, C514S307000, C514S314000, C514S326000, C514S361000, C514S365000, C514S372000, C514S374000, C514S378000, C514S381000, C514S396000, C514S397000, C514S254050, C514S266240, C544S011000, C544S132000, C544S060000, C544S180000, C544S237000, C544S238000, C544S058500, C544S284000, C544S333000, C544S353000, C544S405000, C544S370000, C546S114000, C546S115000, C546S118000, C546S148000, C546S176000, C546S208000, C546S272700, C548S131000, C548S134000, C548S136000, C548S143000, C548S146000, C548S206000, C548S

Reexamination Certificate

active

06982264

ABSTRACT:
The invention relates to substituted alcohol compounds of the formula (I):wherein X, R1, R2, R3, RN, R20and RCare defined herein. The compounds are useful in the treatment or prevention of Alzheimer's disease and more specifically to compounds that are capable of inhibiting beta-secretase, an enzyme that cleaves amyloid precursor protein to produce amyloid beta peptide (A-beta), a major component of the amyloid plaques found in the brains of Alzheimer's sufferers.

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