Isolated nucleic acid molecules encoding human drug...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S252300, C435S320100, C435S325000, C435S069100, C435S006120, C435S015000, C536S023200, C530S350000, C436S094000

Reexamination Certificate

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06987014

ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.

REFERENCES:
patent: 2004/0029125 (2004-02-01), Policky et al.
patent: 2004/0029221 (2004-02-01), Baker et al.
patent: WO 01/79468 (2001-10-01), None
Mackenzie, P. I. J. Biol.Chem. 261:6119-6125, 1986 (TrEMBL accesion No. A42233, 1992).
Jin, C. J. et al. Biochem. Biophys. Res. Commun. 194:496-503, 1993 (TrEMBL accesion No. O75614, 1998).
Sambrook and Russell, Molecular Cloning, Third Edition, CSHL Press, 2001.
U.S. Appl. No. 60/197,590, Policky et al., filed Apr. 2000.

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