Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2006-05-02
2006-05-02
Desai, Rita (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S060000
Reexamination Certificate
active
07038075
ABSTRACT:
The present invention relates to a production method of (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid which comprises optical resolution of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid with an optically active amine of the formula (VIII)wherein R2is 3,4-dimethoxyphenyl or 2-chlorophenyl. According to the present invention, (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid useful as a starting material of a pharmaceutical agent can be efficiently produced with a high optical purity and a relatively high total yield.
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Itaya Nobushige
Iwasaki Mitsuhiro
Katsura Tadashi
Maeda Hiroshi
Matsui Kozo
Desai Rita
Leydig , Voit & Mayer, Ltd.
Reyes Hector M.
Sumitomo Chemical Company Limited
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