Essential downstream component of the wingless signaling...

Details Essential downstream component of the wingless signaling... Essential downstream component of the wingless signaling...

2006-05-23

2006-05-23

Epps-Ford, Janet L. (Department: 1635)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S001000, C530S300000, C530S324000, C530S350000, C424S178100

Reexamination Certificate

active

07049290

ABSTRACT:
An isolated polypeptide comprising a peptide which consists of a legless homology domain (HD); wherein the peptide inhibits Lgs function in colon cancer cells; and a composition comprising the same, are disclosed.

REFERENCES:
patent: WO 01/57188 (2001-08-01), None
Roose et al. Synergy Between Tumor Supressor APC and the B-catenin-Tcf4 Target Tcf1. Science, vol. 285, Sep. 17, 1999, pp. 1923-1926.

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