Method for the purification, recovery, and sporulation of...

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S243000, C435S258100, C435S947000

Reexamination Certificate

active

06984378

ABSTRACT:
A vaccine for in ovo vaccination against avian coccidiosis produced by a method including obtaining the coccidial oocysts from a fecal suspension, homogenizing the fecal suspension, separating the oocysts from the fecal debris by either salt flotation using sodium sulfate or gas flotation using air, sporulating the oocysts using hydrogen peroxide and air sparging, bleaching the sporulated oocysts, washing the bleached oocysts, concentrating the sterile washed oocysts and combining the concentrates of various species of coccidial oocysts, and producing a vaccine. The method in whole or in part can be applied to other kinds of encysted protozoa to produce vaccines for various types of animals.

REFERENCES:
patent: 3147186 (1964-09-01), Edgar
patent: 3617529 (1971-11-01), Thompson et al.
patent: 3617539 (1971-11-01), Grutsch et al.
patent: 3827557 (1974-08-01), Fischer
patent: 4040388 (1977-08-01), Miller
patent: 4208282 (1980-06-01), Becker
patent: 4301148 (1981-11-01), Shibata et al.
patent: 4357320 (1982-11-01), Apontoweil et al.
patent: 4438097 (1984-03-01), Shirley
patent: 4458630 (1984-07-01), Sharma et al.
patent: 4469047 (1984-09-01), Miller
patent: 4500638 (1985-02-01), Apontoweil et al.
patent: 4505892 (1985-03-01), Apontoweil et al.
patent: 4544548 (1985-10-01), Davis et al.
patent: 4593646 (1986-06-01), Miller et al.
patent: 4639372 (1987-01-01), Murray et al.
patent: 4650676 (1987-03-01), Schenkel et al.
patent: 4681063 (1987-07-01), Hebrank
patent: 4681682 (1987-07-01), White et al.
patent: 4724145 (1988-02-01), Murray et al.
patent: 4735801 (1988-04-01), Stocker
patent: 4751079 (1988-06-01), Burger et al.
patent: 4790943 (1988-12-01), Dunn et al.
patent: 4808404 (1989-02-01), Bhogal
patent: 4863731 (1989-09-01), Davis et al.
patent: 4913826 (1990-04-01), Mannig et al.
patent: 4935007 (1990-06-01), Bafundo et al.
patent: 5004607 (1991-04-01), Ragland et al.
patent: 5006341 (1991-04-01), Davis et al.
patent: 5028421 (1991-07-01), Fredericksen et al.
patent: 5045313 (1991-09-01), Frenkel et al.
patent: 5055292 (1991-10-01), McDonald et al.
patent: 5068104 (1991-11-01), Bhogal et al.
patent: 5106617 (1992-04-01), Federicksen et al.
patent: 5279960 (1994-01-01), Anderson et al.
patent: 5280042 (1994-01-01), Lopes
patent: 5288845 (1994-02-01), Chakraborty et al.
patent: 5311841 (1994-05-01), Thaxton
patent: 5339766 (1994-08-01), Phelps et al.
patent: 5359050 (1994-10-01), Chakraborty et al.
patent: 5661015 (1997-08-01), Binger et al.
patent: 5674484 (1997-10-01), Miller et al.
patent: 5702612 (1997-12-01), Wang
patent: 5807551 (1998-09-01), Reynolds
patent: 6019985 (2000-02-01), Brown et al.
patent: 6231871 (2001-05-01), Coloe
patent: 2098773 (1994-12-01), None
patent: 047662 (1987-12-01), None
patent: 0 256 878 (1988-02-01), None
patent: 256878 (1988-02-01), None
patent: 258045 (1988-03-01), None
patent: 291173 (1988-11-01), None
patent: 0 337 589 (1989-01-01), None
patent: 0 325 359 (1989-07-01), None
patent: 344808 (1989-12-01), None
patent: 109942 (1991-03-01), None
patent: 439056 (1991-07-01), None
patent: 522482 (1993-01-01), None
patent: 650733 (1995-05-01), None
patent: 08268817 (1996-10-01), None
patent: 2019189 (1994-09-01), None
patent: 2094121 (1997-10-01), None
patent: 2095409 (1997-11-01), None
patent: WO 9301276 (1993-01-01), None
patent: WO 9416725 (1994-08-01), None
patent: WO 96/40233 (1996-12-01), None
patent: WO 96/40234 (1996-12-01), None
patent: WO 9712582 (1997-04-01), None
patent: WO 9814212 (1998-04-01), None
patent: WO 8808699 (1998-11-01), None
patent: WO 00/50072 (2000-08-01), None
patent: WO 01/34187 (2001-05-01), None
patent: WO 02/37961 (2002-05-01), None
Fuller, A.L., et al “Analysis of coccidian oocyst populations by means of flow cytometry”, J. Protozool., vol. 36, No. 2, pp. 14 146, 1989.
O'Grady, M.R., et al, “An investigation of variables in a fecal flotation technique”, Can. J. Comp. Med., vol. 44, pp. 148-154, Apr. 1980.
J.F. Ryley, et al.,Parasitology, 73, pp. 311-326, 1976.
Smith P.H., et al. “Froth Flotation For Harvesting Chlorella Algae”; Northwest Science, vol. 42, No. 4, 1968, pp. 165-171.
Bare et al., “Algae removal using dissolved air flotation,”Journal WPCF47(1): 153-169 (1975).
Bass, “Uncinariasis in Mississippi,”J. Amer. med. Ass.47: 185-187 1906).
Davis, “Techniques” 411-458, no date, no source.
Dulski et al, “The Purification of Sporocysts and Sporozoites from Eimeria tennella Oocysts Using Percoll Density Gradients,”Avian Diseases32: 235-239 (1988).
Eckert et al., Editors, “Guidelines on techniques in coccidiosis research,”European Commission1-24 (1995).
Graat et al., “Rate and course of sporulation of oocysts ofEimeria vulinaunder different environmental conditions,”Parasitology108: 497-502 (1994).
Grunnet et al, “Elimination of Ascaris Suum Eggs from Sewage by Air Flotation,”Nord. Vet.-Med.29: 458-459 (1977).
Hammond et al., “An improved method for sporulating oocysts in bovine faecal material,”Amer. J. Vet. Res.5: 70-71 (1944).
Hill et al., “A mechanical apparatus for screening worm eggs from faeces,”J. Parasit.47: 357-362 (1961).
Jackson, “The isolation of viable coccidial sporozoites,”Parasitology54: 87-93 (1964).
Jeston et al., “Comparison of the Infectivity ofEimeria TenellaOocysts Maintained at 4, 12 or 28° C Over Time to Determine the Optimal Storage Temperature,”VIIIth International Coccidiosis Conference(Jul. 2001).
Lane, “The Mass Diagnosis of Ankylostome Infestation (Part I),”Trans. Roy. Soc. Trop. Med. Hyg.16: 274-313 (1923).
Lotze et al., “A practical method for culturing coccidial oocysts in tap water,”J. Parasit.47: 588-590 (1961).
Marquardt et al, “The Effect of Physical and Chemical Agents on the Oocyst ofEimeria zurnii(Protozoa, Coccidia),”J. Protozool7(2): 186-189 (1960).
Marquardt, “Separation of Nematode Eggs from Fecal Debris by Gradient Centrifugation,”The Journal of Parasitology248-250.
Nyberg et al., “Effect of Sodium Hypochlorite on the Oocyst Wall ofEimeria tenellaas Shown by Electron Microscopy,”Proceedings of the Helminthological Society of Washington37(1): 32-36 (1970).
Patnaik, “A Technique of Obtaining Oocysts of Coccidia in Pure State from Chicken Faeces by Modified Marquardt's Method,”The Indian Veterinary Journal414-422, no date-no volume.
Peterson et al., “Replacement of the Medium for a Natural Phytoplankton Community by Tangential-Flow Filtration, with Special Emphasis on Toxicity Tests,”Bull. Environ. Contam. Toxicol.57: 603-609 (1996).
Schmatz et al., “Purification ofEimeriaSporozoites by DE-52 Anion Exchange Chromatography,”J. Protozool31(1):181-183 1984).
Smith et al., “Froth Flotation for Harvesting Chlorella Algae,”Northwest Science42(4): 165-171 (1968).
Vetterling, “Continuous-flow Differential Density Flotation of Coccidial Oocysts and a Comparison with Other Methods,”The Journal of Parasitology55(2): 412-417 (1969).
Whitlock, “The recovery and identification of the first-stage larvae of sheep nematodes,”Aust. vet. J.35: 310-316 (1959).
Wilson et al., “Biochemistry of Sproulation in Oocysts ofEimeria acervulina,” Biochemistry of Sporulation8(4): 410-416 (1961).
“A Cleaning Method for Coccidial Oocysts Using Density-Gradient Sedimentation,”The Journal of Parasitology49(1): 159-160.
International Search Report, PCT/US02/27668: (Date of Mailing: Jan. 13, 2003).
Jeffers, et al.,Embryonic Response to Eimeria Tenella InfectionJ. Parisitol., 56(4), 1970, 656-662.
Fredericksen, et al.,In Ovo Administration of a Potential Recombinant Coccidal Antigen Vaccine in Poultryles Colloques de L'Inra, 49, 1989, 655-660.
Sharma & Burmester,Resistance to Marek's Disease at Hatching in Chickens Vaccinated as Embryos with Turkey HerpesvirusAvian Disease, 26(1), 134-148.
Stedman's Medical Dictionary, 25thEd., 199

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for the purification, recovery, and sporulation of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the purification, recovery, and sporulation of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the purification, recovery, and sporulation of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3574905

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.