Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-03-21
2006-03-21
Coleman, Brenda (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S221000, C540S557000, C540S567000, C540S568000
Reexamination Certificate
active
07015214
ABSTRACT:
The present invention relates to 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones of formula I:or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.
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Houpis et al., Synthesis of a New Generation Reverse Transcriptase Inhibitor via the BC 13/GaCl3-Induced Condensation of Anillines with Nitriles (Sugasawa Reaction), Tetrahedron Letters, 1994, pp. 6811-6814, vol. 35, No. 7.
Tucker et al., Synthesis of a Series of 4-(Arylethynyl)-6-Chloro-4-Cyclopropyl-3,4-Dihydroquinazolin-2(1H)-Ones as Novel Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors, J. Med. Chem., 1994, pp. 2437-2444, vol. 37.
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Bristol-Myers Squibb Pharma Company
Coleman Brenda
VanAtten Mary K.
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