Surface treatment

Details Surface treatment Surface treatment

2006-07-04

2006-07-04

Fredman, Jeffrey (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S006120, C435S007100, C435S287200

Reexamination Certificate

active

07070922

ABSTRACT:
Described is a process for producing a biomolecular monolayer on a biosensor surface comprising the steps of: reacting a biosensor surface with a solution of heterobifunctional reagent having a first functional group and a second functional group, the first functional group being capable of forming a covalent bond to the biosensor surface groups, the second functional group forming a covalent bond with a homobifunctional polymer to obtain a self-assembled monolayer, and thereafter reacting the monolayer with capture molecules.

REFERENCES:
patent: 4812512 (1989-03-01), Buendia et al.
patent: 5510481 (1996-04-01), Bednarski et al.
patent: 6413934 (2002-07-01), Stayton et al.
patent: 2002/0028455 (2002-03-01), Laibinis et al.
patent: 2002/0045277 (2002-04-01), Schmid et al.
patent: 2003/0017508 (2003-01-01), Charych et al.
patent: 1 132 739 (2001-09-01), None
patent: 2324866 (1998-11-01), None
patent: WO 99/17120 (1999-04-01), None
Beier, et al., “Versatile derivatisation of solid support media for covalent bonding on DNA-microchips,” Nucleic Acids Research, 1999, 27(9), 1970-1977.
Chrisey, et al., “Covalent attachment of synthetic DNA to self-assembled monolayer films,” Nucleic Acids Research, 1996, 24(15), 3031-3039.
Zalipsky, S., “Functionalized Poly(ethylene glycol) for Preparation of Biologically Relevant Conjugates,” Bioconjugate Chem, 1995, 6, 150-165.
Copy of PCT Search Report dated Jul. 17, 2004 from corresponding PCT application, PCT/US03/38752.

Affiliated with

Also associated with

Rating

Surface treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Surface treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surface treatment will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3565741