Use of lipopolysaccharides to manage corneal infections and...

Details Use of lipopolysaccharides to manage corneal infections and... Use of lipopolysaccharides to manage corneal infections and...

2006-01-10

2006-01-10

Gitomer, Ralph (Department: 1651)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S012200

Reexamination Certificate

active

06984622

ABSTRACT:
The antibiotic polypeptide β-defensin-2 (hBD-2) is expressed in the eye, and is useful for treating ocular wounds. hBD-2 is increased in the eye upon exposure to lipopolysaccharides (LPS). Administration of LPS to the eye thereby provides a useful method for increasing the amount of this antibiotic peptide in the eye.

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