Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Reexamination Certificate
2006-03-21
2006-03-21
Manuel, George (Department: 3762)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
C435S173700
Reexamination Certificate
active
07016725
ABSTRACT:
The present invention provides a method and apparatus for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. According to the present method the living tissue is subjected to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogenous electric field being induced in the dividing cells. The non-homogenous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular members towards the cleavage furrow causes the break down thereof which results in destruction of the dividing cells, while the non-dividing cells of the living tissue remain intact.
REFERENCES:
patent: 2220269 (1940-11-01), Patzold et al.
patent: 4016886 (1977-04-01), Doss et al.
patent: 4121592 (1978-10-01), Whalley
patent: 4263920 (1981-04-01), Tasto et al.
patent: 4467809 (1984-08-01), Brighton
patent: 4472506 (1984-09-01), Liburdy
patent: 4622952 (1986-11-01), Gordon
patent: 4626506 (1986-12-01), Arnold et al.
patent: 4676258 (1987-06-01), Inokuchi et al.
patent: 4822470 (1989-04-01), Chang
patent: 4846178 (1989-07-01), Fuxue et al.
patent: 4846196 (1989-07-01), Wiksell et al.
patent: 4923814 (1990-05-01), Marshall
patent: 4936303 (1990-06-01), Derwiler et al.
patent: 4971991 (1990-11-01), Umemura et al.
patent: 5099756 (1992-03-01), Franconi et al.
patent: 5158071 (1992-10-01), Umemura et al.
patent: 5236410 (1993-08-01), Granov et al.
patent: 5312813 (1994-05-01), Costerton et al.
patent: 5386837 (1995-02-01), Sterzer
patent: 5389069 (1995-02-01), Weaver
patent: 5441532 (1995-08-01), Fenn
patent: 5441746 (1995-08-01), Chagnon
patent: 5468223 (1995-11-01), Mir
patent: 5606971 (1997-03-01), Sarvazyn
patent: 5674267 (1997-10-01), Mir et al.
patent: 5718246 (1998-02-01), Vona
patent: 5807257 (1998-09-01), Bridges
patent: 5964726 (1999-10-01), Korenstein et al.
patent: 5976092 (1999-11-01), Chinn
patent: 5984882 (1999-11-01), Rosenschein et al.
patent: 6027488 (2000-02-01), Hofmann et al.
patent: 6043066 (2000-03-01), Mangano et al.
patent: 6055453 (2000-04-01), Hofmann et al.
patent: 6068650 (2000-05-01), Hofmann et al.
patent: 6096020 (2000-08-01), Hofmann et al.
patent: 6319901 (2001-11-01), Bernard et al.
patent: 6366808 (2002-04-01), Schroeppel et al.
patent: 6413255 (2002-07-01), Stern
patent: 6447499 (2002-09-01), Gray
patent: 6856839 (2005-02-01), Litovitz
patent: 2002/0193832 (2002-12-01), Gray
patent: 2002/0193833 (2002-12-01), Dimmer et al.
patent: 2003/0060856 (2003-03-01), Chornenky et al.
patent: 0 330 797 (1989-09-01), None
patent: 1 419 660 (1975-12-01), None
patent: 2 026 322 (1980-02-01), None
patent: 2 043 453 (1980-10-01), None
patent: WOO1/60994 (2001-08-01), None
U.S. Appl. No. 10/263,329, filed Oct. 2, 2002, Palti.
U.S. Appl. No. 10/288,562, filed Oct. 31, 2002, Palti.
Hofmann et al., “Electronic Genetic-Physical and Biological Aspects of Cellular Electomanipulation”,IEEE Eng. in Med. and Biology Mag., Dec. 1986,p6-23,New York.
Berg et al., “Electric Field Effects on Biological Membranes:Electoincorporation and Electofusion”,Ettore Maj Inter. Science, 1987,p135-166,vol. 32,Phys. Science,New York.
Asbury et al., “Trapping of DNA in Nonuniform Oscillating Electic Fields”, Biophysical Journal, Feb. 1998, p1024-1030, vol. 74,Seattle,WA.
Kramer Nicole R.
Manuel George
Proskauer Rose LLP
Standen Ltd.
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