Method of enantioselectively catalyzing a reaction

Details Method of enantioselectively catalyzing a reaction Method of enantioselectively catalyzing a reaction

2006-01-24

2006-01-24

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C502S166000, C502S167000, C540S362000, C546S002000, C548S101000, C548S105000, C548S403000, C548S540000, C549S326000, C552S001000, C552S008000, C552S010000, C556S045000, C556S057000, C556S137000, C556S438000, C556S442000, C556S475000, C560S017000, C560S070000, C560S070000, C560S070000, C560S070000, C560S070000

Reissue Patent

active

RE038947

ABSTRACT:
A chiral catalyst is disclosed together with methods of using it for enantioselective syntheses. The chiral catalyst includes a nucleus with two metal atoms that has four bridging ligands oriented radially to the axis of the nucleus. Each of these ligands includes a two complexing atoms each complexed to one of the metal atoms. At least one of the bridging ligands includes a chiral center which is bonded to one of the complexing atoms. Preferably, all four of the bridging ligands include a chiral center bonded to one of the complexing atoms. The catalyst of the invention has been found to be useful in catalyzing carbenoid transformation reactions such as cyclopropanation.

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