Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

Details Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

2006-09-26

2006-09-26

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S467000, C548S468000, C548S486000

Reexamination Certificate

active

07112603

ABSTRACT:
The present invention is directed to prodrugs of certain 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

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