Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-04-04
2006-04-04
McGarry, Sean (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C514S04400A
Reexamination Certificate
active
07022831
ABSTRACT:
The present invention provides novel anticode oligomers and methods of using them for controlling the growth of cancer cells expressing the bcl-2 gene.
REFERENCES:
patent: 4525358 (1985-06-01), Baltes et al.
patent: 4999290 (1991-03-01), Lee
patent: 5015568 (1991-05-01), Tsujimoto et al.
patent: 5098890 (1992-03-01), Gerwitz
patent: 5149628 (1992-09-01), Croce
patent: 5202429 (1993-04-01), Tsujimoto et al.
patent: 5459251 (1995-10-01), Tsujimoto et al.
patent: 5475096 (1995-12-01), Gold et al.
patent: 5478941 (1995-12-01), Cossement et al.
patent: 5585479 (1996-12-01), Hoke et al.
patent: 5750390 (1998-05-01), Thompson et al.
patent: 5831066 (1998-11-01), Reed
patent: 5932697 (1999-08-01), Caceci et al.
patent: 6005095 (1999-12-01), Capaccioli et al.
patent: 6040181 (2000-03-01), Reed
patent: 0 058 146 (1982-08-01), None
patent: 340948 (1989-11-01), None
patent: 0 617 028 (1994-09-01), None
patent: 2 311 940 (1997-01-01), None
patent: WO 9213102 (1992-08-01), None
patent: WO-93/20200 (1993-10-01), None
patent: 94/06430 (1994-03-01), None
patent: WO 94/27426 (1994-12-01), None
patent: WO 96/27663 (1996-09-01), None
K. P. Paul, “ETAC: an Update”, International Journal of Immunopathology and Pharmacology, vol. 10, No. 2, pp. 127-128, 1997.
U. Waln, “Allergic factors associated with the development of asthma and the influence of cetirizine in a double-blind, randomised, placebo-controlled trial: First results of ETAC”, Pediatric Allergy and Immunology, vol. 9, No. 3, pp. 116-124, Aug. 1998.
L. Fasce et al., “Cetirizine Reduces ICAM-I on Epithelial Cells during Nasal Minimal Persistent Inflammation in Asymptomatic Children with Mite-Allergic Asthma”, Int. Arch. Allergy Immunol. vol. 109, No. 3, pp. 272-276, 1996.
A. Brik et al., “Effect of cetirizine, a new histamine H1antagonist, on airway dynamics and responsiveness to inhaled histamine in mild asthma”, vol. 80, No. 1, pp. 51-56, 1987.
J.O. Warner et al, “Determinants of total and specific IgE in infants with atopic dermatitis”, Pediatric Allergy and Immunology, vol. 8, pp. 177-184, Nov. 1997.
J.H. Dijkman et al., “Prophylactic treatment of grass pollen-induced asthma with cetirizine”, Clinical and Experimental Allergy, vol. 20, pp. 483-490, Sep. 1990.
C. De Vos et al., “Antihistamines and allergic asthma”, Allergie et Immunologie, vol. 23, No. 9, pp. 396-401, Nov. 1991.
D. Tashkin et al., “Cetirizine inhibition of histamine-induced bronchospasm”, vol. 59, pp. 49-52, Dec. 1987.
G. Bruttmann et al., “Protective effect of cetirizine in patients suffering from pollen asthma”, Annals of Allergy, vol. 64, pp. 224-228, Feb. 1990.
H. Redier et al., “Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma”, Journal of Allergy and Clinical Immunology, vol. 90, No. 2, pp. 215-224, Aug. 1992.
J.B. Wasserfallen et al., “Effect of cetirizine, a new H1antihistamine, on the early and late allergic reactions in a bronchial provocation test with allergen”, Journal of Allergy and Clinical Immunology, vol. 91, No. 6, pp. 1189-1197, Jun. 1993.
J.A. Grant et al., “Safety and efficacy of cetirizine (CET) in the prophylactic management of patients with seasonal allergic rhinitis (SAR) and asthma”, vol. 91, No. 1, p. 197, Mar. 12-17, 1993.
“Medical researchers aim at fundamental better protection and treatment of the atopic child”, ETAC Science, pp. 1-8, Jan. 1994.
“Asthma prevention in risk children: Cetirizine”, pp. 61-62, 1995.
I. Trieloff , “Early treatment of the atopic child”, pp. 390-391, 1995.
“The role of early intervention in childhood asthma therapy”, pp. 8224-8227, 1998.
E. Bidat et al., “The treatment of childhood asthma”, pp. 3021-3026, 1991.
L. Businco et al., “From atopic dermatitis to asthma”, pp. 477-481, 1997.
B. Schwarz, “Treatment with cetirizine also for children”, p 34, 1993.
S. Matsubara et al., “Effect of betotastine basilate on experimental asthma model in guinea pigs”, pp. 31-36, 1997.
Toshiyuki Miyashita et al., Cancer Research, vol. No. 52, pp. 5407-5411, Oct. 1, 1992.
Toshiyuki Miyashita et al., Blood, vol. No. 81, pp. 151-157, Jan. 1, 1993.
J. C. Reed et al., Annals of Oncology, 1993, Page Nos. 61-65.
F. E. Cotter et al., Oncogene, vol. No. 9, pp. 3049-3055, Oct. 1994.
Shinichi Kitada et al., Antisense Research and Development, vol. 4, pp. 71-79, Summer 1994.
Shinichi Kitada et al., Antisense Research and Development, vol. 3, pp. 157-169, Summer 1993.
Reed et al., Cancer Res., 50, p. 5656, 1990.
Williams, Cell 65, p. 1097, 1991.
Strasser et al., Cell 67, p. 889, 1991.
Patent Cooperation Treaty (PCT) International Search Report dated Jan. 12, 1995.
C. Paoletti, “Anti-Sense Oligonucleotides as Potential Antitumour Agents: Prospective Views and Preliminary Results,” Anti-Cancer Drug Design, vol. 2, pp. 325-331, 1988.
Stein et al., “Oligodeoxynucleotides as Inhibitors of Gene Expression: A Review,” Cancer Research, vol. 48, pp. 2659-2668, May 15, 1988.
Eugen Uhlmann et al., “Antisense Oligonucleotides: A New Therapeutic Principle,” Chemical Reviews, vol. 90, No. 4, pp. 544-584, Jun. 1990.
Tsujimoto, Y., et al., Proc. Natl. Acad. Sci. USA, vol. 83, pp. 5214-5218, Jul. 1986.
Negrini, M., et al., Cell, vol. 49, pp. 455-463, 1987.
Reed, J., et al., Science, vol. 236, pp. 1295-1299, Jun. 5, 1987.
Orkin SH, et al., “Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy”.
D. M. Hockenbery. et al. “BCL2 protein is topographically restricted in tissues characterized by apoptotic cells”, Proc. Natl. Acad. Sci. USA, vol. 88, 1991, pp. 6961-6965.
B. Calabretta, “Inhibition of Protooncogene Expression and Antisense Ologodeoxynycleotides: Biological and Therapeutic Implications”, Cancer Research, vol. 51, No. 17, Sep. 1, 1991, pp. 4505-4510.
Darby & Darby
McGarry Sean
The Trustees of the University of Pennsylvania
Vivlemore Tracy
LandOfFree
Regulation of BCL-2 gene expression does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Regulation of BCL-2 gene expression, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Regulation of BCL-2 gene expression will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3541851