Antidepressant azaheterocyclylmethyl derivatives of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S300000, C514S321000, C514S338000, C546S115000, C546S113000, C546S277400, C546S197000

Reexamination Certificate

active

06987117

ABSTRACT:
Compounds of the formulauseful for the treatment of depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse, and dysthymia.

REFERENCES:
patent: 5468767 (1995-11-01), Cipollina et al.
patent: 5532241 (1996-07-01), Bottcher et al.
patent: 5741789 (1998-04-01), Hibschman et al.
patent: 5750724 (1998-05-01), Kang et al.
patent: 5869490 (1999-02-01), Stack
patent: 5977106 (1999-11-01), Patoiseau et al.
patent: 2002/0183355 (2002-12-01), Tran et al.
patent: 0 559 285 (1993-09-01), None
patent: WO 95/07274 (1995-03-01), None
patent: WO 96/24596 (1996-08-01), None
patent: WO 99/05140 (1999-02-01), None
patent: WO 01/14330 (2001-03-01), None
patent: WO 01/49680 (2001-07-01), None
Wijngaarden et al. Recl. Trav. Chim. Pays-Bas, 1993, 112:126-130.
Barnes et al. Neuropharmacology, 1999, 38: 1083-1092.
Fletcher et al. Psychopharmacology, 1990, 100(2): 188-94.
Matuszewich et al. Brain Research 1999, 820(1-2): 55-62.
Birch, A.M., “N-substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D2antagonists/5-HT1Apartial agonits with potential as atypical antipsychotic agents,”J. Med. Chem., 1999, 42, 3342-3355.
Artigas, F., et al., “Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors,”Arch. Gen. Psychiatry, 1994, 248-251.
Blier, P., et al., “Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression,”J. of Clinical Psychopharmacology, 1995, 15(3), 217-222.
Bundgaard, H., et al., “(C) Means to enhance penetration; (1) Prodrugs as a means to improve the delivery of peptide drugs,”Advanced Drug Delivery Reviews, 1992, 8, 1-38.
Bundgaard, H., “Design and Application of Prodrugs,”Texbook of Drug Design and Development, Krogsgaard-Larsen, P., et al. (Eds.),1991, Chap. 5, 114-123.
Hall, M.D., et al., “[3H]8-hydroxy-2-(Di-n-Propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain,”J. Neurochem., 1985, 44(6), 1685-1696.
Lazareno, S., et al., “Pharmacological characterization of acetylcholine-stimulated [35S]-GYPγS binding mediated by human muscarinic m1-m4 receptors: antagonist studies,”Br. J. Pharmacol., 1993, 109, 1120-1127.
Perez, V., “Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment,”The Lancet, 1997, 349, 1594-1597.
Tome, M.B., et al., “Serotonergic autoreceptor blockage in the reduction of antidepressant latency: personality variables and response to paroxetine and pindolol,”J. Affect Discord, 1997, 44, 101-109.
Tome, M.B., et al., “Paroxetine and pindolol: a randomized trial of serotonergic autoreceptor blockade in the reduction of antidepressant latency,”Int. Clin. Psychopharmacol., 1997, 12, 81-89.
Wilen, S.H., et al., “Strategies in optical resolutions,” Tetrahedron Report No. 38,Tetrahedron, 1977, 33, 2725-2736.
Wilen, S.H., “Tables of Resolving Agents and Optical Resolutions,”Univ. of Notre Dame Press, Notre Dame, IN, E.L. Eliel (Ed.), 1972, p. 268-298.

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