In-vivo diagnostic method by means of near infrared radiation

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S001110, C424S009100, C424S001650

Reexamination Certificate

active

07025949

ABSTRACT:
This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.

REFERENCES:
patent: 4945239 (1990-07-01), Wist et al.
patent: 5153112 (1992-10-01), Yoshida et al.
patent: 5298379 (1994-03-01), Adin et al.
patent: 5880287 (1999-03-01), Dandliker et al.
patent: 6083485 (2000-07-01), Licha et al.
patent: 6238931 (2001-05-01), Buechler et al.
patent: 6258340 (2001-07-01), Licha et al.
patent: 6319488 (2001-11-01), Licha et al.
patent: 6329531 (2001-12-01), Turner et al.
patent: 6534041 (2003-03-01), Licha et al.
patent: 6630570 (2003-10-01), Licha et al.
patent: 2002/0022004 (2002-02-01), Licha et al.
patent: 2003/0026763 (2003-02-01), Licha et al.
patent: 0709463 (1968-07-01), None
patent: 2910760 (1980-04-01), None
patent: 3828360 (1990-02-01), None
patent: 3912046 (1990-03-01), None
patent: 4136769 (1993-05-01), None
patent: 4323368 (1995-01-01), None
patent: 8404665 (1984-12-01), None
patent: 8910758 (1989-11-01), None
patent: 9010219 (1990-09-01), None
patent: 9118006 (1991-11-01), None
patent: 9200748 (1992-01-01), None
“New Photosensitizers for the Photodynamic Therapy of Tumors”, Bonnet R.,SPIE, vol. 2078 (1994) pp. 1-17.
“Optical Imaging Reborn with Technical Advances”, Benaron, David A.,Diagnostic Imaging(1994) pp. 69-76.
“Antibody-Indocyanin Conjugates for Immunophotodetection of Human Squamous Cell Carcinoma in Nude Mice”, Silvio Folli et al.,Cancer Research, vol. 54 (1994) pp. 2643-2649.
“Cyanine Dye Labeling Reagents: Sulfoindocyanine Succinimidyl Esters”, Mujumdar, Ratnaker B. et al.,Bioconjugate Chemistry, vol. 4, No. 2 (1993) pp. 105-111.
“Synthesis, Spectral Properties and Photostabilities of Symmetrical and Unsymmetrical Squaraines; A New Class of Fluorophores with Long-Wavelength Excitation and Emission”, Terpetschnig, Ewald et al.,Analytical Chemistry(1993) Abstract, p. 633.
“An Investigation of Squaraines as a New Class of Fluorophores with Long-Wavelength Excitation and Emission”, Terpetsching, Ewald et al.,Journal of Fluorescensevol. 3, No. 3 (1993) Abstract, p. 153.
“Laser Mammography Using NIR-Light”, Klingenbeck, K. et al.,Gynäkol Geburtshilfliche Rundsch(1993) 33 (Suppl 1) pp. 299-300.
“Intraoperative Florescein Angiography”, Googe, J.M. et al.,Opthalmology, vol. 100, No. 8 (1993) pp. 1167-1170.
“Determination of Plasma Volume and Total Blood Volume Using Indocyanine Green: A Short Review”, Busse, M.W. et al.,Journal of Medicine, vol. 24, No. 1, (1993) pp. 10-27.
“Evaluation of Near Infrared Dyes as Labels for Immunoassays Utilizing Laser Diode Detection: Development of Near Infrared Dye Immunoassay (Nirdia)”, Boyer, A.E. et al.,Analytical Letters, vol. 25, No. 3, (1992) pp. 415-428.
“Single Laser Three Color Immunofluorescence Staining Procedures Based on Energy Transfer Between Phycoerythrin and Cyanine 5”, Lansdorp, Peter M. et al.,Cytometry, vol. 12 (1991) pp. 723-730.
Lightscanning Versus Mammography for the Detection of Breast Cancer in Screening and Clinical Practice, Alveryd, A. et al.,Cancer, vol. 65 (1990) pp. 1671-1677.
“Cyanine Dye Labeling Reagents for Sulfhydryl Groups”, Ernst, Lauren A. et al.,Cytometry, vol. 10 (1989) pp. 3-10.
“Laser-Induced Autofluorescence of Human Arteries”, Satori, Michele et al.,Circulation Research, vol. 63, No. 6 (1988) pp. 1053-1059.
“Contrast in Diaphanography of the Breast”, Navarro, Glenis A. et al.,Medical Physics, vol. 15, No. 2 (1988) pp. 181-187.
“IR-Diaphanoscopy in Medicine”, Beuthan, J. et al.,Medical Optical Tomography: Functional Imaging and Monitoring, vol. IS11 (1993) pp. 263-282.
“Tricarbocyanines with Hydrocarbon Rings in the Chromophore”, Slominskii et al.,Ukrainskii Khimicheskii Zhurnal, vol. 40, No. 6, pp. 61-64.
“The Role of Excited Singlet Molecular Oxygen in the Photodegradation of Functional Squarylium Dyes”, Kuramoto, N.,JSDC, vol. 106 (1990) pp. 181-186.
“Synthesis and Characterization of Deep-coloured Squarylium Dyes for Laser Optical Recording Media”, Kuramoto et al.,Dyes and Pigments, vol. 11 (1989) pp. 21-35.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

In-vivo diagnostic method by means of near infrared radiation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with In-vivo diagnostic method by means of near infrared radiation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In-vivo diagnostic method by means of near infrared radiation will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3538531

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.