Human uncoupling proteins and polynucleotides encoding the same

Details Human uncoupling proteins and polynucleotides encoding the same Human uncoupling proteins and polynucleotides encoding the same

2006-01-17

2006-01-17

Weber, Jon (Department: 1653)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C435S069100, C435S320100, C435S252300, C435S455000, C530S350000, C530S300000

Reexamination Certificate

active

06987178

ABSTRACT:
The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described uncoupling proteins (UCPs).

REFERENCES:
patent: 4190496 (1980-02-01), Rubenstein et al.
patent: 4215051 (1980-07-01), Schroeder et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4873191 (1989-10-01), Wagner et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5075217 (1991-12-01), Weber
patent: 5364759 (1994-11-01), Caskey et al.
patent: 5399346 (1995-03-01), Anderson et al.
patent: 5625048 (1997-04-01), Tsien et al.
patent: 5702902 (1997-12-01), Tartaglia
patent: 5741666 (1998-04-01), Tartaglia
patent: 5780280 (1998-07-01), Lebkowski et al.
patent: 5824544 (1998-10-01), Armentano et al.
patent: 5827703 (1998-10-01), Debs et al.
patent: 5830727 (1998-11-01), Wang et al.
patent: 5837458 (1998-11-01), Minshull et al.
patent: 5840710 (1998-11-01), Lee et al.
patent: 5843742 (1998-12-01), Natsoulis et al.
patent: 5846528 (1998-12-01), Podsakoff et al.
patent: 5853975 (1998-12-01), Tartaglia
patent: 5858740 (1999-01-01), Finer et al.
patent: 6403784 (2002-06-01), Turner et al.
patent: 2003/0073623 (2003-04-01), Drmanac et al.
patent: WO98/03243 (1998-01-01), None
patent: WO 9831396 (1998-07-01), None
patent: WO 9845313 (1998-10-01), None
patent: WO 9845438 (1998-10-01), None
patent: WO98/50542 (1998-11-01), None
Hyseq Inc., US20030073623A1, sequence alignment.
Bird et al, 1988, “Single-Chain Antigen-Binding Proteins”, Science 242:423-426.
Bitter et al. 1987, “Expression and Secretion Vectors for Yeast”. Methods in Enzymology 153:516-544.
Butler, J.E., 1981, “The Amplified ELISA: Principles of and Applications for the Comparative Quantitation of Class and Subclass Antibodies and the Distribution of Antibodies and Antigens in Biochemical Separates”, Meth. Enzymol. 73:482-523.
Colbere-Garapin et al, 1981, “A New Dominant Hybrid Selective Marker for Higher Eukaryotic Cells”, J. Mol. Biol. 150:1-14.
Cote et al, 1983, “Generation of human monoclonal antibodies reactive with cellular antigens”, Proc. Natl. Acad. Sci. USA 80:2026-2030.
Gautier et al, 1987, “α-DNA IV:α-anomeric and β-anomeric letrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physiochemical properties and poly (rA) binding”, Nucleic Acids Research 15(16):6625-6641.
Gordon, 1989, “Transgenic Animals”, Intl. Rev. Cytol. 115:171-229.
Greenspan et al, 1993, “Idiotypes: structure and immunogenicity”, FASEB Journal 7:437-444.
Gu et al, 1994, “Deletion of a DNA Polymerase βGene Segment in T Cells Using Cell Type-Specific Gene Targeting”, Science 265:103-106.
Huse et al, 1989, “Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda”, Science 246:1275-1281.
Huston et al, 1988, “Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced inEscherichia coli”, Proc. Natl. Acad. Sci. USA 85:5879-5883.
Inoue et al, 1987, “Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and R Nase H”, FEBS Letters 215(2):327-330.
Inoue et al, 1987, “Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides”, Nucleic Acids Research 15(15):6131-6149.
Inouye & Inouye, 1985, “Up-promoter mutations in the lpp gene ofEscherichia coli”, Nucleic Acids Research 13(9):3101-3110.
Janknecht et al, 1991, “Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus”, Proc. Natl. Acad. Sci. USA 88:8972-8976.
Kohler and Milstein, 1975, “Continuous cultures of fused cells secreting antibody of predefined specificity”, Nature 256:495-497.
Lakso et al, 1992, “Targeted oncogene activation by site-specific recombination in transgenic mice”, Proc. Natl. Acad. Sci. USA 89:6232-6236.
Lavitrano et al, 1989, “Sperm Cells as Vectors for Introducing Foreign DNA into Eggs: Genetic Transformation of Mice”, Cell 57:717-723.
Lo, 1983, “Transformation by Iontophoretic Microinjection of DNA: Multiple Integrations without Tandem Insertions”, Mol. & Cell. Biology 3(10):1803-1814.
Logan et al, 1984, “Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection”, Proc. Natl. Acad. Sci. USA 81:3655-3659.
Lowy et al, 1980, “Isolation of Transforming DNA: Cloning the Hamster aprt Gene”, Cell 22:817-823.
Miyajima et al, 1986, “Expression of murine and human granulocyte-macrophase colony-stimulating factors inS. cerevisiae: mutagenesis of the potential glycosvlation sites”, EMBO J. 5:6. 1193-1197.
Mulligan & Berg, 1981, “Selection for animal cells that express theEscherichia coligene coding for xanthine-guanine phosphoribosyltransferase”, Proc. Natl. Acad. Sci. USA 78(4):2072-2076.
Neuberger et al, 1984, “Recombinant antibodies possessing novel effector functions”, Nature 312:604-608.
Nisonoff, 1991, “Idiotypes: Concepts and Applications”, J. of Immunology 147:2429-2438.
O'Hare et al, 1981, “Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase”, Proc. Natl. Acad. Sci. USA 78(3):1527-1531.
Platt, et al., 1994, “Independent Regulation of Adipose Tissue-specificity and Obesity Response of the Adipsin Promoter in Transgenic Mice”, J. Biol. Chem. 269:28558-28562.
Ruther et al, 1983, “Easy identification of cDNA clones”, EMBO Journal 2(10): 1791-1794.
Santerre et al, 1984, “Expression of prokaryotic genes for hygromycin B and G418 resistance as dominant-selection markers in mouse L cells”, Gene 30:147-156.
Sarin et al, 1988, “Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates”, Proc. Natl. Acad. Sci. USA 85:7448-7451.
Smith et al, 1983, “Molecular Engineering of the Autographa californica Nuclear Polyhedrosis Virus Genome: Deletion Mutations within the Polyhedrin Gene”, J. Virol. 46(2):584-593.
Stein et al, 1988, “Physiochemical properties of phosphorothioate oligodeoxynucleotides”, Nucleic Acids Research 16(8):3209-3221.
Szybalska & Szybalski, 1962, “Genetics of Human Cell Lines, IV. DNA-Mediated Heritable Transformation of a Biochemical Trait”, Proc. Natl. Acad. Sci. USA 48:2026.
Takeda et al, 1985, “Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences”, Nature 314:452-454.
Thompson et al, 1989, “Germ Line Transmission and Expression of a Corrected HPRT Gene Produced by Gene Targeting in Embryonic Stem Cells”, Cell 56:313-321.
Van Der Putten et al, 1985, “Efficient insertion of genes into the mouse germ line via retroviral vectors”, Proc. Natl. Acad. Sci. USA 82:6148-6152.
Van Heeke & Schuster, 1989, “Expression of Human Asparagine Synthetase inEscherichio coli”, J. Biol. Chem. 264:5503-5509.
Voller, A. et al, 1978, “Enzyme immunoassays with special reference to ELISA techniques”, J. Clin. Pathol. 31:507-520.
Ward et al, 1989, “Binding activities of a repertoire of single immunoglobulin variable domains secreted fromEscherichia coli”, Nature 341:544-546.
Wigler et al, 1977, “Transfer of Purified Herpes Virus Thymidine Kinase Gene to Cultured Mouse Cells”, Cell 11:223.
Wigler et al, 1980, “Transformation of mammalian cells with an amplifiable dominant-acting gene”, Proc. Natl. Acad. Sci. USA 77(6):3567-3570.
Database Embl Nucleotide and Protein Sequences, 1998, XP002141168 Hinxton, GB, Soares

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