Sulfone derivatives as 5-HT7 receptor ligands

Details Sulfone derivatives as 5-HT7 receptor ligands Sulfone derivatives as 5-HT7 receptor ligands

2006-09-05

2006-09-05

Owens, Amelia A. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S112000

Reexamination Certificate

active

07101892

ABSTRACT:
The present invention relates to sulfone derivatives of formula (I):in-line-formulae description="In-line Formulae" end="lead"?Ar—SO2—CR2R3-L-N(R1)2Iin-line-formulae description="In-line Formulae" end="tail"?wherein Ar, L, R1, R2and R3are as defined herein, and pharmaceutically acceptable salts and N-oxides thereof, useful in the treatment of a condition which is susceptible to treatment by modulation of 5-HT7receptor activity, such as depression or a sleep disorder.

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