Piperidine amides as modulators of chemokine receptor activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S381000, C514S397000, C514S406000, C514S422000, C514S428000, C544S333000, C546S197000, C546S199000, C546S276400, C548S250000, C548S314700, C548S364100, C548S517000, C548S518000, C548S567000

Reexamination Certificate

active

06984651

ABSTRACT:
The present application describes modulators of CCR3 of formula (I):or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.

REFERENCES:
patent: 4613695 (1986-09-01), Carlsson et al.
patent: 5352796 (1994-10-01), Hoeger et al.
patent: 5668151 (1997-09-01), Poindexter et al.
patent: 5847148 (1998-12-01), Jacobsen et al.
patent: 5880128 (1999-03-01), Doll et al.
patent: 5994364 (1999-11-01), Njoroge et al.
patent: 5998447 (1999-12-01), Stilz et al.
patent: 2614189 (1977-10-01), None
patent: 0685463 (1994-02-01), None
patent: 0842943 (1997-11-01), None
patent: 0842945 (1997-11-01), None
patent: 659743 (1998-06-01), None
patent: 0903349 (1999-03-01), None
patent: 915088 (1999-05-01), None
patent: 92/03410 (1992-03-01), None
patent: 9301167 (1993-01-01), None
patent: 93/06108 (1993-04-01), None
patent: 93/21172 (1993-10-01), None
patent: 95/09859 (1995-04-01), None
patent: 95/13069 (1995-05-01), None
patent: 95/24186 (1995-09-01), None
patent: 96/14317 (1996-05-01), None
patent: 96/16981 (1996-06-01), None
patent: 97/09329 (1997-03-01), None
patent: 97/12876 (1997-04-01), None
patent: 9714689 (1997-04-01), None
patent: 97/23458 (1997-07-01), None
patent: 97/24325 (1997-07-01), None
patent: 98/04247 (1998-02-01), None
patent: 98/11092 (1998-03-01), None
patent: 98/25604 (1998-06-01), None
patent: 98/31359 (1998-07-01), None
patent: 98/31669 (1998-07-01), None
patent: WO 98/53814 (1998-12-01), None
patent: 99/50238 (1999-10-01), None
patent: WO 99/54321 (1999-10-01), None
patent: 00/00477 (2000-01-01), None
patent: 00/35449 (2000-06-01), None
patent: 00/35451 (2000-06-01), None
patent: 00/35452 (2000-06-01), None
patent: 00/35453 (2000-06-01), None
patent: 00/35454 (2000-06-01), None
patent: 00/35876 (2000-06-01), None
patent: 00/35877 (2000-06-01), None
patent: WO 01/00206 (2001-01-01), None
Wyngaarden et al. “Cecil textbook of medicine” Saunders, p. 1397-98 (1983).
Ikegami et al. “Preparation of azepine . . . ” CA 135:137529 (2001).
Atwal et al., “Binding of ATP-Sensitive Potassium Channel (KATP) Openers to Cardiac Membranes: Correlation of Binding Affinities with Cardioprotective and Smooth Muscle Relaxing Potencies”, J. Med. Chem., vol. 41, pp. 271-275, 1998.
Michael Gutschow, “One-Pot Reactions of N-(Mesyloxy)phthalimides with Secondary Amines to 2-Ureidobenzamides, 2-Ureidobenzoic Acids, Ethyl 2-Ureidobenzoates, or Isatoic Anhydrides”, J. Org. Chem, vol. 64, pp. 5109-5115, 1999.
Jacobsen et al., Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloprotease Inhibitors, Journal of Medicinal Chemistry, 1999, pp. 1525-1536, vol. 42, No. 9.
Freidinger et al., Novel Glutamic Acid Derived Cholecystokinin Receptor Ligands, Journal of Medicinal Chemistry, 1990, pp. 591-595, vol. 33, No. 2.
Capet et al., “Pyrrolidinines derivatives with a strong binding affinity for CCK and gastrin receptors”, CA 122:31320 (1994).
Adams et al., “Early trauma polymorphonuclear neutrophil responses to chemokines are associated with development of sepsis, pneumonia, and organ failure”, CA 136:261758 (2001).
Stedman's medical dictionary (2000), p. 897-898.
Harrison's principles of internal medicine (1994), p. 494-495.

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