Nucleic acid and amino acid sequences relating to...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023200, C536S023100, C536S023500, C536S023700, C435S320100, C435S069100, C435S252300, C435S325000, C435S069600, C435S004000, C435S006120

Reexamination Certificate

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07041814

ABSTRACT:
The invention provides isolated polypeptide and nucleic acid sequences derived fromEnterobacter cloacaethat are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

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French et al., Sequence and Properties of Pentaerythritol Tetranitrate Reductase fromEnterobacter cloacaePB2,Journal of Biothecnology, Nov. 1996, p. 6623-6627.
Ehrhardt et al., Sequencing analysis of Four NewEnterobacter ampD Allels,Antimicrobial Agents and Chemotherapy, Aug. 1996, p. 1953-1956.
Hou et al., Ribotyping and Random Amplification of Polymorphic DNA for NosocomialEnterobacter cloacaeIsolates in a Pediatric Intensive Care Unit,Concise Communications, vol. 18, No. 11, p. 769-771, Nov. 1997.
Deguchi et al., Detection of Mutations in the gyrA and parC genes in quinolone-resistant clinical isolates ofEnterobacter cloacae, Journal of Antimicrobial Chemotherapy, vol. 40, p. 543-549.

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