Human smooth muscle myosin heavy chain

Details Human smooth muscle myosin heavy chain Human smooth muscle myosin heavy chain

2005-12-13

2005-12-13

Steadman, David (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

Reexamination Certificate

active

06974688

ABSTRACT:
The invention provides novel compositions, methods, and uses of hSMMyHC polypeptides and polynucleotides.

REFERENCES:
patent: WO 96/23069 (1996-01-01), None
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Abaza et al. (1992) J Prot Chem 11:433-444.
Manstein et al. (1995) J Mus Res Cell Mot 16:325-332.
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“Myosin, Heavy Chain 11, Smooth Muscle; MYH11”, OMIM ID No.: 160745, Nov. 2001.
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“The Fusion Gene Cbfb-MYH11 Blocks Myeloid Differentiation and Predisposes Mice to Acute Myelomonocytic Leukaemia”, Castilla, L.H. et al., Nat Genet Oct. 23, 1999, pp 144-146.
“Smooth Muscle Myosin Heavy Chain Locus (MYH11) maps to 16p13.13-p13.12 and Estabilshes a New Region of Conserved Synteny Between Human 16p and mouse 16”, Denz, Z et al., Genomics 1993, Oct. 18, pp 156-159.
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Babu, Philip et al. “Characterization of a mammalian smooth muscle myosin heavy-chain gene: Complete nucleotide and protein coding sequence and analysis of the 5' end of the gene” Proc. Natl. Acad. Sci. USA, Dec., 1991, pp. 10676-10680, vol. 88.

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