Low-cost method and apparatus for non-invasively measuring...

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

Reexamination Certificate

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C600S322000

Reexamination Certificate

active

06968221

ABSTRACT:
A method and apparatus for measuring a blood analyte concentration using an inexpensive, low precision sensor device is provided. One embodiment of the method includes obtaining energy absorption measurement data through a body part of an individual. A plurality of indicator variables are subsequently calculated from the energy absorption measurement data. An indicator variable from the plurality of indicator variables having the highest correlation to blood glucose level is determined, and a first optical term based on the indicator variable with the highest correlation to blood glucose level is allocated to form a regression analysis equation. An estimated value of the blood analyte concentration using the regression analysis equation is calculated.

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Jungheim, Karsten et al., “Glucose Monitoring at the Arm, Diabetes Care, Risky delays of hypoglycemia and hyperglycemia detection,” Diabetes Care, vol. 25(6):956-960, Jun. 2002.
Ellison, John M. et al., “Rapid Changes in Postprandial Blood Glucose Produce Concentration Differences at Finger, Forearm, and Thigh Sampling Sites,” Diabetes Care, vol. 25(6):961-964, Jun. 2002.

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