Triaryl-ethylene derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

5142378, 5142388, 514255, 514315, 514317, 514331, 514357, 514408, 514428, 514649, 514651, 514824, 544165, 544174, 544396, 546229, 546336, 548569, 548575, 564323, 564324, 564325, 564326, A61K 31135, C07C21128

Patent

active

055256333

ABSTRACT:
The present invention relates to novel triaryl-ethylene derivatives that are useful as anti-neoplastic agents, antiatherosclerotic agents, and hypocholesterolemic agents.

REFERENCES:
patent: 2914563 (1959-11-01), Allen et al.
patent: 3247252 (1966-04-01), Palopoli et al.
patent: 3634517 (1972-01-01), Palopoli et al.
patent: 4623660 (1986-11-01), Richardson
Murphy et al., "Structural Requirements for Binding of Anti estrogens" etc., Rational Basis for Chemotherapy pp. 195-210, (1983), Alan R. Lisa, Inc. ed., NY.
Watts et al., "Microsonal Binding Sites, etc," J of Biological Chemistry (1984), vol. 259, #7 pp. 4223-4229.
Palopoli III, "Substituted Aminoalkoxy trianylhaloethylenes," J. Med. Chem , vol. 10, pp. 84-86 (1967).
Palopoli, et al., J. Med. Chem., 10:84-86 (Jan./1967).
Murphy, et al., Biochemical and Biophysical Research Communications, vol. 100(3):1353-1360 (Jun. 16, 1981).
Hecker, et al., Europ. J. Cancer, 10:747-749 (1974).
Herbst, et al., Cancer Chemotherapy Reports, 43:39-41 (Dec./1964).
Murphy, et al., J. of Clinical Endocrinology and Metabolism 57(2):373-379 (1983).
Murphy, et al., Ludwig Institute for Cancer Research (Sydney Branch), AU, Rational Basis for Chemotherapy, pp. 195-210, 1983, Alan R. Lisa, Inc., ed., N.Y.
Clark, et al., Pharm. Ther, vol. 15:467-519 (1982).
Legha, et al., Cancer Treatment Reviews, 3:205-216 (1976).
Watts, et al., Jour. of Biological Chemistry, vol. 259(7), 4223-4229 (1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Triaryl-ethylene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triaryl-ethylene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triaryl-ethylene derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-351952

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.