Dipeptide derivatives

Details Dipeptide derivatives Dipeptide derivatives

1991-06-24

1993-03-16

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544114, 544121, 544123, 544129, 544130, 544131, 544133, 544139, 544140, 544141, 544145, 544147, 544148, 544149, 544152, 544158, 544163, 544165, 544164, 544168, C07D41312, C07D26530

Patent

active

051946084

ABSTRACT:
A dipeptide derivative of formula (I) is provided, which is capable of inhibiting the enzymatic activity of renin and thereby depressing the renin-angiotensin system and lowering the blood pressure. ##STR1## wherein: R.sup.1 is C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, aryl, or heterocyclic radical;

REFERENCES:
patent: 4791102 (1988-12-01), Bernat et al.

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