Compounds and compositions for delivering active agents

Details Compounds and compositions for delivering active agents Compounds and compositions for delivering active agents

2005-12-06

2005-12-06

Zucker, Paul A. (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

C562S455000

Reexamination Certificate

active

06972300

ABSTRACT:
Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides, such as rhGH. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration, are provided, and methods of preparation of the modified amino acid compound are provided.

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Leone-Bay, Andrea, et al., “N-Acylated a-Amino Acids as Novel Oral Delivery Agents for Proteins”, Journal of Medicinal Chemistry, vol. 31, No. 21, 1995, pp. 4263-4269.

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