Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-12-27
2005-12-27
Kemmerer, Elizabeth C. (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S253300, C435S254110, C435S320100, C435S325000, C530S300000, C530S350000, C536S023100, C536S023500
Reexamination Certificate
active
06979559
ABSTRACT:
The present invention encompasses three full length nucleic acid and amino acid sequences for PolyValent Cation-Sensing Receptors (PVCR) in Atlantic Salmon. These PVCR have been named SalmoKCaR#1, SalmoKCaR#2, and SalmoKCaR#3. The present invention includes homologs thereof, antibodies thereto, and methods for assessing SalmoKCaR nucleic acid molecules and polypeptides. The present invention further includes plasmids, vectors, host cells containing the nucleic acid sequences of SalmoKCaR #1,2 and/or 3.
REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 5545808 (1996-08-01), Hew et al.
patent: 5763569 (1998-06-01), Brown et al.
patent: 5858684 (1999-01-01), Nemeth et al.
patent: 5962314 (1999-10-01), Brown et al.
patent: 5981599 (1999-11-01), Moe et al.
patent: 6001884 (1999-12-01), Nemeth et al.
patent: 6337391 (2002-01-01), Harris et al.
patent: 6463882 (2002-10-01), Harris, Jr. et al.
patent: 6463883 (2002-10-01), Harris, Jr. et al.
patent: 6475792 (2002-11-01), Harris, Jr. et al.
patent: 6481379 (2002-11-01), Harris, Jr. et al.
patent: 6564747 (2003-05-01), Harris, Jr. et al.
patent: 2003/0082574 (2003-05-01), Harris, Jr. et al.
patent: 2003/0124657 (2003-07-01), Harris et al.
patent: 2003/0232366 (2003-12-01), Harris et al.
patent: 1784152 (1992-12-01), None
patent: WO 9735977 (1997-10-01), None
patent: WO 02/30182 (2002-04-01), None
patent: WO 02/031149 (2002-04-01), None
patent: WO 03/030639 (2003-04-01), None
Doerks et al., (Jun. 1998) “Protein annotation: detective work for function prediction.” Trends in Genetics 14(6): 248-250.
Smith and Zhang (Nov. 1997) “The challenges of genome sequence annotation or ‘The devil is in the details’.” Nature Biotechnology 15:1222-1223.
Brenner (Apr. 1999) “Errors in genome annotation.” Trends in Genetics 15(4): 132-133.
Bork and Bairoch (Oct. 1996) “Go hunting in sequence databases but watch out for the traps.” Trends in Genetics 12(10): 425-427.
Wells (Sep. 18, 1990) “Additivity of Mutational Effects in Proteins.” Biochemistry 29(37): 8509-8517.
Ngo et al. (Mar. 2, 1995) “The Protein Folding Problem and Tertiary Structure Prediction, Chapter 14: Computational Complexity Protein Structure Prediction, and the Levinthal Paradox” pp. 433-506.
Bork (2000) “Powers and Pitfalls in Sequence Analysis: The 70% Hurdle.” Genome Research 10:398-400.
Skolnick and Fetrow (2000) “From gene to protein structure and function: novel applications of computational approaches in th genomic era.” Trends in Biotech. 18(1): 34-39.
Naito, T., et al., “Putative pheromone receptors . . . ,”Proc. Natl. Acad. Science, 95: 5178-5181 (1998).
Clark, M.S., et al., “Sparus aurata mRNA . . . ,”EMBL Databse Accession No.: AJ289717(Jun. 9, 2001).
Nearing, J., “Polyvalent cation receptor . . . ,”PNAS, 99(14): 9231-9236 (2002).
Nearing, J. et al., “Cloning and Expression of a homologue . . . ,”Journal of The American Society of Nephrology, 8: 40A. (From ASN Program and Abstracts, 1997, Abstract No. A0194) (1997).
Baum, M.S., et al., “An apical extracellular Calcium/Polyvalent cation sensing receptor (CaR)present in the osmoregulatory organs of salt water (SW) and fresh water (FW) fish likely plays a role in salinity adaptation,”Journal of Am. Society of Nephrology7(9): p. 1276 (1996).
Riccardi, D., et al., “Cloning and Functional Expression of a Rat Kidney Extracellular Calcium/Polyvalent cation-Sensing Receptor,”Proc. Nat. Acad. Sci.USA, 92: 131-135 (1995).
Brown, E.M., et al., “Calcium-Ion-Sensing Cell-Surface Receptors,”The New England Journal of Medicine, 333(4): 234-240 (1995).
Brown, E.M., et al., “Cloning and Characterization of an Extracellular Ca2+-Sensing Receptor from Bovine Parathyroid,”Nature, 366:575-580 (1993).
Brown, E.M., et al., “Neomycin mimics the Effects of HighExtracellular Calcium Concentration on Parathyroid Function in Dispersed Bovine Parathyroid Cells,”Endocrinology, 128(6): 3047-3054 (1991).
Sands, J.M., et al., “Apical Extracellular Calcium/Polyvalent Cation-sensing Receptor Requlates Vasopressin-elicited Water Permeability in Rat Kidney Inner Medullary Collecting Duct,”J. Clinical Investigation, 99(6): 1399-1405 (1997).
Garrett, J.E.,et al., “Molecular Cloning and Functional Expression of Human Parathyroid Calcium Receptor cDNAs,”Journal of Biological Chemistry, 270(21): 12919-12925 (1995).
Sands, A.T., et al., “High Susceptibility to Ultraviolet-Induced Arcinogenesis in Mice Lacking XPC,”Nature, 377: 162-165 (1995).
Aida, K., “Molecular Cloning of a PutativeCa2+Sensing Receptor cDNA from Human Kidney,”Biochemical&Biophysical Research Communications, 214(2): 524-529(1995).
Ward, D.T., et al., “Disulfide-bonds in the extracellular calcium-polyvalent cation sensing receptor mediate dimer formation and its response to divalent cations in vitro,”J. Bio. Chemistry,273: 14476-14483 (1998).
Radman, DP, et al., “Evidence for calcium Receptor mediated stanniocalcin secretion in fish,”Molecular and Cellulare Endocrinology, 186: 111-119 (2002).
Abnet, C.C., et al., “Two forms of aryl hydrocarbon receptor type 2 in rainbow trout (Oncorhynchus mykiss),”J. of Biological Chemistry, 274: 15159-15166 (1999).
Usher, M. L., et al., Effects of transfer to seawater on growth and feeding in Atlantic salmon smolts (Salmo salarL.),Aquaculture, 94: 309-326 (1991).
Morkore, T., and Rorvik, K., “Seasonal variations in growth, feed utilisation and product quality of farmed Atlantic salmon (Sakni sakar) transferred to seawater as 0+ smolts or 1 + smolts,”Aquaculture, 199: 145-157 (2001).
Johnston, I. A., et al., “Muscle fibre density in relation to the colour and texture of smoked Atlantic salmon (Salmo salarL.),”Aquaculture, 189: 335-349 (2000).
Pace, A.J.,et al., “Dimerization of the calcium-sensing receptor occurs within the extracellular domain and is eliminated by cys to Ser mutations at Cys101 and Cys236,”J. Biol. Chemistry, 274: 11629-11634 (1999).
Bai, M., et al., “Expression and characterization of inactivating and activating mutations in the human Ca2+0-sensing receptor,”J. Biol. Chemistry, 271(32): 19537-19545 (1996).
Pearce, S.H.S., et al., “Functional characterization of calcium-sensing receptor mutations expressed in human embryonic kidney cells,”J. Clin. Invest., 98: 860-1866 (1996).
Ray, K., et al., “The carboxyl terminus of the human calcium receptor. Requirements for cell surface expression and signal transduction,”J. Biol. Chem., 272: 31355-31361 (1997).
Gama, L. and Breitwieser, “A carboxyl-terminal domain controls the cooperativity for extracellular Ca2+activation of the human calcium sensing receptor. A study with receptor-green fluorescent protein fusions,”J. Biol. Chemistry, 273: 29712-29718 (1998).
Ho, C., et al., “A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism,”Nature(Genetics), 11: 389-394 (1995).
Pollak, M.R., et al., “Mutations in the Human Ca2+-Sensing Receptor Gene Cause Familial Hypocalciuric Hypercalcemia and Neonatal Severe Hyperparathryoidism”,Cell, 75: 1297-1303 (1993).
Malaga-Trillo, E. and A. Meyer, “Genome duplicatins and acceleratied evolution of Hox gene and cluster architecture in teleost fishes,” American Zoology , 41: 676-686 (2001).
Lopreato, G.F., et al., “Evolution and divergence of sodim channel genes in verterbrates,”Proc. Nat. Acad. Sci., 98: 7588-7592 (2001).
Chen, TT, et al., “Transgenic Fish,”Trends in Biotechnology, 8: 209-215 (1990).
Takeo, J. and S. Yamashita, “Two distinct isoforms of cDNA encoding rainbow trout androgen receptors,”J. Biol. Chem, 274 5674-5680 (1999).
Robinson-Rechavi, M., et al., “An Ancestral whole-genom
Betka Marlies
Harris, Jr. H. William
Nearing Jacqueline
Hamilton Brook Smith & Reynolds P.C.
Kemmerer Elizabeth C.
MariCal, Inc.
Nichols Christopher James
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