6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S457000, C549S400000

Reexamination Certificate

active

06908942

ABSTRACT:
The present invention provides (i) 6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran derivatives; (ii) a process for synthesizing benzopyran derivatives with high efficiency by parallel synthesis on a solid-phase as one of combinatorial chemical synthesis technologies; and (iii) a use of the benzopyran derivatives for preventing and treating diseases or disorders induced by promotion of lipid peroxidation or accumulation of oxidized products.

REFERENCES:
patent: 6555574 (2003-04-01), Tanikawa et al.
I. Sziráki et al., “Manganese: A Transition Metal Protects Nigrostriatal Neurons From Oxidative Stress In The Iron-Induced Animal Model Of Parkinsonism,” Neurosci. 85, 1998, pp. 1101-1111.
Y. Goodman, et al., “K+ channel openers protect hippocampal neurons against oxidative injury and amyloid β-peptide toxicity,” Brain Research 706, 1996, pp. 328-332.

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