Maspin transcriptional regulatory sequences and uses thereof

Details Maspin transcriptional regulatory sequences and uses thereof Maspin transcriptional regulatory sequences and uses thereof

2005-11-01

2005-11-01

Eyler, Yvonne (Department: 1642)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S325000

Reexamination Certificate

active

06960658

ABSTRACT:
Isolated nucleic acid molecules that include transcriptional regulatory sequences of the maspin gene are described. These nucleic acid molecules are useful for identifying compounds and proteins that alter expression of maspin in mammary cells and other cell types.

REFERENCES:
patent: 5470970 (1995-11-01), Sager et al.
Verma IM, et al. Nature 1997 Sep 18; 389 (6648): 239-42.
Memorandum, Department of Health & Human Services, “Serious Adverse Event in a Study of Gene Transfer in X-Linked severe Combined Immunodeficiency”, Jan. 14, 2003.
Pandha HS, et al. Curr Opin Invest Drugs 2000; 1 (1): 122-34.
Amalfitano A, et al. Curr Gene Ther 2002; 2: 111-33.
Houdebine LM. J Biotechnol May 31, 1994; 34 (3): 269-87.
Maas N, et al. Tumor Diagnostk und Therapie 1997; 18 (4): 89-96.
Zhang M, et al. Cell Growth and Differentiation Feb. 1997; 8 (2): 179-186.
Zhang M, et al. Proc Natl Acad Sci USA May 27, 1997; 94 (11) 5673-5678
Zou Z, et al. J Biol Chem Mar. 3, 2000; 275 (9): 6051-6054.
Liotta et al., “Cancer Metastasis and Angiogenesis: An Imbalance of Positive and Negative Regulation” Cell 64(2):327-336, 1991.
Sager et al., “Maspin: A tumor Suppressing Serpin” Curr. Top. In Microbiol. And Immunol. 213(1):51-64, 1996.
Sheng et al., “Production, Purification, and Characterization of Recombinant Maspin Proteins” J. of Biol. Chem. 269(40):30988-30993, 1994.
Zou et al., “Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells” Science 263:441-580, 1994.

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