Method of purification of molecules using unbranched...

Details Method of purification of molecules using unbranched... Method of purification of molecules using unbranched...

2005-11-22

2005-11-22

Wax, Robert A. (Department: 1653)

Liquid purification or separation

Processes

Chromatography

C210S635000, C210S198200, C210S500340, C210S500350, C560S001000, C560S352000, C930S120000, C530S344000

Reexamination Certificate

active

06966992

ABSTRACT:
The current invention provides methods for molecule purification by RP-LC and RP-HPLC that uses unbranched terminal alkyldiols as eluting solvents. In particular, the present invention purifies molecules, particularly proteins and peptides, on reverse phase liquid chromatography columns using a buffer containing either 1,5 pentanediol, 1,6 hexanediol or 1,7 heptanediol.

REFERENCES:
patent: 5693769 (1997-12-01), Kahne et al.
patent: 5801039 (1998-09-01), Maurer et al.
patent: 5994511 (1999-11-01), Lowman et al.
patent: 6008041 (1999-12-01), Frye et al.
patent: 6437101 (2002-08-01), Hayenga et al.
Varkey et al. J. Peptide Res. 51, 49-54 (1998).
Yu et al. J. Chromatography A, 725, 149-155(1996).
Arakawa et al. Arch. Biochem. Biophys. 224(1):169-177 (1983).

Affiliated with

Also associated with

Rating

Method of purification of molecules using unbranched... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of purification of molecules using unbranched..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of purification of molecules using unbranched... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3498448