Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-11-08
2005-11-08
Morris, Patricia L. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S215000, C546S225000, C546S226000, C546S227000, C546S228000, C546S237000, C546S238000
Reexamination Certificate
active
06962998
ABSTRACT:
Disclosed are a method for producing racemic piperidine derivatives by processing optically-active piperidine derivatives in a hydrogen atmosphere in the presence of a reducing catalyst; and a method for producing optically-active piperidine derivatives or their acid salts by optically resolving the racemic piperidine derivatives obtained in the former method.
REFERENCES:
patent: 63-185943 (1988-08-01), None
patent: 06-135906 (1994-05-01), None
patent: 96/09290 (1996-03-01), None
Clas Sonesson et al., “An Efficient Synthesis of the Novel Dopamine Autoreceptor Antagonist S-(-)-OSU6162, via Palladium Catalyzed Cross-Coupling Reaction,”Tetrahedron Letters, (1994), vol. 35, No. 48, pp. 9063-9066.
Hans Malmberg et al, Lithium Methylorganocuprates Containing Chiral 2-(N-Methyl-2-pyrrolidinyl)-, 2-(N-Methyl-2-piperidinyl)-or 2-(1-N,N-Dimethylaminoethyl)-phenyl Groups. A Comparison of Addition to Two Acyclic Enones,Acta Chemica Scandinavica B 35, (1981), pp. 625-629.
Sonesson, C. et al, “Substituted (S)-Phenylpiperidines and Rigid Congeners as Preferential Dopamine Autoreceptor Antaagonists: Synthesis and Structure-Activity Relationships, ”J. Med. Chem.,1994, vol. 37, pp. 2735-2753.
Fujino Toshihiro
Sato Haruyo
Morris Patricia L.
Piper Rudnick LLP
Toray Industries Inc.
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