Ocular analyte sensor

Details Ocular analyte sensor Ocular analyte sensor

2005-12-27

2005-12-27

Kremer, Matthew J (Department: 3736)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S321000

Reexamination Certificate

active

06980842

ABSTRACT:
An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety which is displaced from the receptor moiety by the analyte is measured and provides a means of determining analyte concentration in an ocular fluid, such as tears, aqueous humor, or interstitial fluid. The concentration of the analyte in the ocular fluid, in turn, indicates the concentration of the analyte in a fluid or tissue sample of the body, such as blood or intracellular fluid.

REFERENCES:
patent: 4987065 (1991-01-01), Stavrianopoulos et al.
patent: 5929033 (1999-07-01), Tang et al.
patent: 6120460 (2000-09-01), Abreu
patent: 6214566 (2001-04-01), Asa et al.

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