Antiadipose topical treatment composition based on garlic...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from allium

Reexamination Certificate

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Details

C424S725000, C514S860000

Reexamination Certificate

active

06852343

ABSTRACT:
The invention relates to an antiadipose topical treatment composition comprising an effective amount of at least one antiadipose active agent chosen from extracts ofAllium sativumbulbs, with the exception of an oleoresin extracted with hexane, and a cosmetically or pharmaceutically acceptable excipient which is suitable for topical application for external use—especially on the skin. The invention covers the uses of this composition and of its extracts cosmetically for treating cellulite and localized dermal excess adipose, and therapeutically for treating obesity.

REFERENCES:
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patent: 4338336 (1992-11-01), None
S. Klaus, “Functional Differentiation of White and Brown Adipocytes”, RG 002, Bio Essays, vol. 19, No. 3, pp. 215-223, Dec. 23, 1996.
S. Farmer et al., “Insights Into the Transcriptional Control of Adipocyte Differentiation”, RG 005, Journal of Cellular Biochemistry Supplements, 32/33, pp. 59-67, 1999.
M.D. Lane et al., “Regulated Expression of the Obese Product (leptin) in White Adipose Tissue and 3T3-L1 Adipocytes”, Proc. Natl. Acad. Sci. USA, vol. 92, pp 9034-9037, Sep. 1995.
J. N. Dhuley et al., “Hypolipidaemic and Antioxidant Activity of Diallyl Disulfide in Rats”, Royal Pharmaceutical Society of Great Britain, 1999 XP-002173644, Abstract only.
Derwent Publications Ltd., London, GB, AN 2000-489113, XP-002173645 & KP 99 055 308 A (LG CHEM), Jul. 15, 1999.

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