Gloucose-regulated mRNA instability element

Details Gloucose-regulated mRNA instability element Gloucose-regulated mRNA instability element

2005-02-08

2005-02-08

Falk, Anne-Marie (Department: 1632)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S004000, C435S006120, C435S320100, C435S455000, C536S024100

Reexamination Certificate

active

06852529

ABSTRACT:
The subject invention pertains to nucleic acid constructs for post-transcriptional control of expression of a ploynucleotide encoding a protein in a eukaryotic cell, wherein the constructs include a metabolite responsive instability element such as the glucose-regulated mRNA instability element. The subject invention further pertains to host cells and vectors comprising the nucleic acid constructs of the invention, as well as probes, methods, and kits for detecting metabolite responsive instability elements or mutations thereof.

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