Polynucleotides encoding methionyl tRNA synthetase from...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023100, C536S023200, C435S320100, C435S252300, C435S254110, C435S325000, C435S419000

Reexamination Certificate

active

06903204

ABSTRACT:
The invention providesStaphylococcus aureusmethionyl tRNA synthetase polypeptides and DNA (RNA) encodingStaphylococcus aureusmethionyl tRNA synthetase polypeptides and methods for producing such poypeptides by recombinant techniques. Also provided are methods for utilizingStaphylococcus aureusmethionyl tRNA synthetase polypeptides for the protection against infection, particularly bacterial infections.

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Bult et al. (1996) Complete Genome Sequence of the Methanogenic Archaeon,Methanococcus jannaschii.Science 273(5278): 1058-1073.
Bult et al.Methanococcus jannaschiifrom bases 1205576 to 1215558 (section 109 of 150) of the complete genome. Genbank submission U67567/L77117 made Aug. 20, 1996.
Georgiou (1988) Optimizing the Production of Recombinant Proteins in Microorganisms. AIChE J. 34(8): 1233-1248.
Kron, et al., “An immunodominant antigen ofBrugia malayiis an asparaginyl-tRNA synthetase”,FEBS Letters, 374pp. 122-124 (1995).
Chalker, et al., “Analysis and toxic overexpression inEscherichia coliof astaphylococcalgene encoding isoleucyl-tRNA synthetase”,Gene, 141,pp. 103-108 (1994).
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