Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-11
2005-10-11
Kumar, Shailendra (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S318000
Reexamination Certificate
active
06953857
ABSTRACT:
The present invention relates to compounds comprising the following formula:in-line-formulae description="In-line Formulae" end="lead"?R0—Q—X—Q′—W—U—V—G—M (I)in-line-formulae description="In-line Formulae" end="tail"?These compounds are useful as pharmacologically active compounds. They exhibit an antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders such as thromboembolic diseases or restenoses. These compounds are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can generally be used to treat, prevent, or cure conditions in which an undesired activity of factor Xa and/or factor VIIa is present, or where inhibition of factor Xa and/or factor VIIa is intended. The invention further relates to processes for the preparation of these compounds, methods of their use (e.g., as active ingredients in pharmaceuticals), and pharmaceutical preparations comprising them.
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Gerlach Uwe
Matter Hans
Nazare Marc
Peyman Anuschirwan
Will David William
Aventis Pharma Deutschland GmbH
Kumar Shailendra
Rossi Joseph D.
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