Treatment of immune diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Details

C536S023100, C536S023520

Reexamination Certificate

active

06906041

ABSTRACT:
The invention concerns the use of a nucleic acid capable of expressing beta-interferon for the preparation of a pharmaceutical composition for the treatment of an immune disease.

REFERENCES:
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patent: 6359054 (2002-03-01), Lemieux et al.
Youssef et al. The Journal of Immunology 161:3870-3879, 1998.
Hernberg et al., Lyphocytes subsets as prognostic markers for cancer patients receiving immunomodulative therapy. 1999. Medical Oncology, vol. 16, pp. 145-153
Martino et al., Cytokine therapy in immune-mediated demyelinating diseases of the central nervous systems a novel gene therapy approach 2000 Jouranl of Neuroimmunology, vol. 107, pp. 184-190.
Crystal, Transfer of Genes to Humans: Early Lessons and Obstacles to Success, Oct. 20, 1995. Science vol. 270 pp. 404-409.
Anderson Human gene therapy Apr. 30, 1998 vol. 392 Nature pp. 25-30.
Triantaphyllopoulos et al. Cloning and expression of murine IFNB and a TNF antagonist for gene therapy of experimental allergic encephalomtelitis pp. 253-263 1998.
Ludovic et al. Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-Cationic liposome complex into the central nervous system1 pp. 5181-5187 1998.
Triantaphyllopoulos et al. Amelioration of collagen-induced arthritis and suppression of interferon-y, interleukin-13 and tumor necrosis factor a production by interferon-B gene therapy pp. 90-99 1999.
Deonarain Ligand-targeted receptor-mediated vectors for gene delivery pp 53-69 1998.
Verma et al. Gene therapy promises, problems and prospects pp. 239-242 vol. 389 1997.

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